Genetics insight for COVID-19 susceptibility and severity: a review

I Fricke-Galindo, R Falfán-Valencia - Frontiers in immunology, 2021 - frontiersin.org
Coronavirus disease (COVID-19) presents a broad spectrum of clinical manifestations
ranging from an asymptomatic to a severe clinical course. The host genetic background …

Association between HLA genotypes and COVID-19 susceptibility, severity and progression: a comprehensive review of the literature

F Migliorini, E Torsiello, F Spiezia, F Oliva… - European Journal of …, 2021 - Springer
The COVID-19 pandemic has markedly impacted on cultural, political, and economic
structures all over the world. Several aspects of its pathogenesis and related clinical …

[HTML][HTML] Epigenome-wide association study of COVID-19 severity with respiratory failure

MC de Moura, V Davalos, L Planas-Serra… - …, 2021 - thelancet.com
Background Patients infected with the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …

Serum troponin, D‐dimer, and CRP level in severe coronavirus (COVID‐19) patients

AM Ali, HM Rostam, MH Fatah… - Immunity …, 2022 - Wiley Online Library
Background Abnormal inflammation coagulation biomarker levels of troponin, C‐reactive
protein (CRP), and D‐dimer levels in serum have been demonstrated to be associated and …

Human genetic basis of coronavirus disease 2019

H Deng, X Yan, L Yuan - Signal transduction and targeted therapy, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in considerable …

The complexity of SARS-CoV-2 infection and the COVID-19 pandemic

MK da Silva Torres, CDA Bichara… - Frontiers in …, 2022 - frontiersin.org
The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) led to the death of millions of people worldwide and thousands more infected individuals …

Association of HLA gene polymorphism with susceptibility, severity, and mortality of COVID‐19: a systematic review

P Deb, K Zannat, S Talukder, AH Bhuiyan, MSA Jilani… - Hla, 2022 - Wiley Online Library
HLA is crucial for appropriate immune responses in several viral infections, as well as in
severe acute respiratory syndrome coronavirus‐2 (SARS CoV‐2). The unpredictable nature …

HLA variation and SARS-CoV-2 specific antibody response

D Wolday, CYJ Fung, G Morgan, S Casalino… - Viruses, 2023 - mdpi.com
Differences in SARS-CoV-2-specific immune responses have been observed between
individuals following natural infection or vaccination. In addition to already known factors …

HLA-C* 04: 01 affects HLA class I heterozygosity and predicted affinity to SARS-CoV-2 peptides, and in combination with age and sex of Armenian patients contributes …

A Hovhannisyan, V Madelian, S Avagyan… - Frontiers in …, 2022 - frontiersin.org
The novel SARS-CoV-2 coronavirus infection has become a global health concern, causing
the COVID-19 pandemic. The disease symptoms and outcomes depend on the host …

Current HLA investigations on SARS-CoV-2 and perspectives

V Douillard, EC Castelli, SJ Mack, JA Hollenbach… - Frontiers in …, 2021 - frontiersin.org
The rapid, global spread of the SARS-CoV-2 virus during the current pandemic has
triggered numerous efforts in clinical and research settings to better understand the host …