Today, it is well-known that the interactions and secretion within the tumour are crucial to
consider for cancer therapy. Some novel cancer therapy modalities such as immunotherapy …

Cancer therapy through anticancer drugs and radiotherapy is associated with several side
effects as well as tumor resistance to therapy. The genotoxic effects of chemotherapy and …

Background: Ovarian cancer progression and invasiveness are promoted by a range of
soluble factors released by cancer cells and stromal cells within the tumor …

Stimulating antitumor immunity is an attractive idea for suppressing tumors. CD4+ and CD8+
T cells as well as natural killer cells (NK) are the primary antitumor immune cells in the tumor …

Immune reactions are involved in both tumour and normal tissue in response to therapy.
Elevated secretion of certain chemokines, exosomes and cytokines triggers inflammation …

The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor
malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage …

Tumor-associated macrophages (TAMs) play a pivotal role in the progression and
resistance of tumors to different anticancer drugs. TAMs can modulate the tumor …

Immune system interactions within the tumour have a key role in the resistance or
sensitization of cancer cells to anti-cancer agents. On the other hand, activation of the …

Oral cancers are among the common head and neck malignancies. Different anticancer
therapy modalities such as chemotherapy, immunotherapy, radiation therapy, and also …

Cancer resistance to therapy is a big issue in cancer therapy. Tumours may develop some
mechanisms to reduce the induction of cell death, thus stimulating tumour growth. Cancer …