The clinical importance of nephron mass

VA Luyckx, BM Brenner - Journal of the American Society of …, 2010 - journals.lww.com
Abundant evidence supports the association between low birth weight (LBW) and renal
dysfunction in humans. Anatomic measurements of infants, children, and adults show …

Nephron number, hypertension, renal disease, and renal failure

WE Hoy, MD Hughson, JF Bertram… - Journal of the …, 2005 - journals.lww.com
Essential hypertension is one of the most common dis-eases in the Western world, affecting
about 26.4% of the adult population, and it is increasing (1). Its causes are heterogeneous …

[HTML][HTML] Reduced nephron number and glomerulomegaly in Australian Aborigines: a group at high risk for renal disease and hypertension

WE Hoy, MD Hughson, GR Singh, R Douglas-Denton… - Kidney international, 2006 - Elsevier
Aborigines in remote areas of Australia have much higher rates of renal disease, as well as
hypertension and cardiovascular disease, than non-Aboriginal Australians. We compared …

Very low birth weight is a risk factor for secondary focal segmental glomerulosclerosis

JB Hodgin, M Rasoulpour, GS Markowitz… - Clinical Journal of the …, 2009 - journals.lww.com
Background and objectives: Low birth weight (LBW), resulting from intrauterine growth
retardation (IUGR) or prematurity, is a risk factor for adult hypertension and chronic kidney …

Effect of intrauterine growth restriction on kidney function at young adult age: the Nord Trøndelag Health (HUNT 2) Study

S Hallan, AM Euser, LM Irgens, MJJ Finken… - American journal of …, 2008 - Elsevier
BACKGROUND: The hypothesis of intrauterine origin of adult disease is debated. We tested
whether intrauterine growth restriction is associated with later kidney function. STUDY …

Salt sensitivity of children with low birth weight

GD Simonetti, L Raio, D Surbek, M Nelle, FJ Frey… - …, 2008 - Am Heart Assoc
Compromised intrauterine fetal growth leading to low birth weight (< 2500 g) is associated
with adulthood renal and cardiovascular disease. The aim of this study was to assess the …

Reduced renal length and volume 20 years after very preterm birth

MG Keijzer-Veen, AS Devos, M Meradji, FW Dekker… - Pediatric …, 2010 - Springer
Intrauterine growth retardation is presumed to be associated with decreased renal size and
impaired renal function as a result of stunted kidney development and nephron deficit. To …

[HTML][HTML] Low nephron number and its clinical consequences

VA Luyckx, K Shukha, BM Brenner - … Maimonides medical journal, 2011 - ncbi.nlm.nih.gov
Epidemiologic studies now strongly support the hypothesis, proposed over two decades
ago, that developmental programming of the kidney impacts an individual's risk for …

Familial factors, low birth weight, and development of ESRD: a nationwide registry study

P Ruggajo, R Skrunes, E Svarstad, R Skjærven… - American Journal of …, 2016 - Elsevier
Background Previous studies have demonstrated that low birth weight (LBW) is associated
with higher risk for end-stage renal disease (ESRD). However, both LBW and ESRD cluster …

Assessment of long-term renal complications in extremely low birth weight children

P Kwinta, M Klimek, D Drozdz, A Grudzień, M Jagła… - Pediatric …, 2011 - Springer
We assessed the long-term renal complications in a regional cohort of extremely low birth
weight (ELBW) children born in 2002–2004. The study group, comprising 78 children born …