Evaluation of hemaPEN® sampling device for measurement of cocaine and metabolites in capillary blood by LC-MS/MS
M Smidt, MF Bastiani, RZ Hahn, L Lima Feltraco Lizot… - Bioanalysis, 2022 - Taylor & Francis
Background: Dried blood spot sampling has been reported for on-site collection of
specimens, but measurements are affected by blood hematocrit, and special handling is …
specimens, but measurements are affected by blood hematocrit, and special handling is …
Analysis of conventional and nonconventional forensic specimens in drug-facilitated sexual assault by liquid chromatography and tandem mass spectrometry
N Almofti, A Ballesteros-Gómez, S Rubio… - Talanta, 2022 - Elsevier
The incidence of drug-facilitated sexual assault (DFSA) has dramatically increased in the
last decades. Forensic analytical scientists continuously seek new methods and specimens …
last decades. Forensic analytical scientists continuously seek new methods and specimens …
Reengineering of albumin-fused cocaine hydrolase CocH1 (TV-1380) to prolong its biological half-life
Therapeutic treatment of cocaine toxicity or addiction is a grand medical challenge. As a
promising therapeutic strategy for treatment of cocaine toxicity and addiction to develop a …
promising therapeutic strategy for treatment of cocaine toxicity and addiction to develop a …
Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene
A majority of cocaine users also consume alcohol. The concurrent use of cocaine and
alcohol produces the pharmacologically active metabolites cocaethylene and …
alcohol produces the pharmacologically active metabolites cocaethylene and …
[HTML][HTML] Effects of alcohol on metabolism and toxicity of cocaine in rats
As most cocaine users drink alcohol, it is interesting to understand how a non-lethal dose of
alcohol affects the metabolism and toxicity of cocaine. In this study, we examined the …
alcohol affects the metabolism and toxicity of cocaine. In this study, we examined the …
SPE-UHPLC-ESI-MS/MS Analysis of Cocaine and Its Metabolites in Conventional and Alternative Biological Specimens: Application to Real Samples
HS Makhdoom, S Afzal, K Sultana, SNH Shah… - ACS …, 2024 - ACS Publications
An increase in cocaine abuse has been observed globally since the past decade. Cocaine
is among the commonly abused stimulants used for recreational purposes. In this study, the …
is among the commonly abused stimulants used for recreational purposes. In this study, the …
Cocaine, crack cocaine, and ethanol: A deadly mix
ET Shimomura, GF Jackson, BD Paul - Critical Issues in Alcohol and Drugs …, 2019 - Elsevier
Abusing cocaine and alcohol at the same time is a deadly combination due to the formation
of a unique metabolite of cocaine, cocaethylene (CE). In contrast to benzoylecgonine (BZ) …
of a unique metabolite of cocaine, cocaethylene (CE). In contrast to benzoylecgonine (BZ) …
Cocaine in different matrices: recent updates on pretreatment and detection techniques
Y Song, Y Zhang, L Wang, C Hu, ZF Liu… - Critical Reviews in …, 2024 - Taylor & Francis
Cocaine abuse has attracted increased attention in the recent past since it can cause
addiction and great harm to the normal human body. Due to cocaine exists in various …
addiction and great harm to the normal human body. Due to cocaine exists in various …
Effects of cebranopadol on cocaine-induced hyperactivity and cocaine pharmacokinetics in rats
Cebranopadol is known as a highly potent analgesic. Recent studies also demonstrated that
administration of cebranopadol significantly decreased cocaine self-administration and …
administration of cebranopadol significantly decreased cocaine self-administration and …
Transesterification of Indazole-3-carboxamide synthetic cannabinoids: identification of metabolite biomarkers for diagnosing co-abuse of 5F-MDMB-PINACA and …
Z Wang, CY Fong, EML Goh, HY Moy… - Journal of Analytical …, 2022 - academic.oup.com
Concurrent use of alcohol with synthetic cannabinoids (SCs) has been widely recorded
among drug abusers. The susceptibilities of three indazole-3-carboxamide type SCs with …
among drug abusers. The susceptibilities of three indazole-3-carboxamide type SCs with …