[PDF][PDF] Overview of the anatomy, physiology, and pharmacology of the autonomic nervous system.

EA Wehrwein, HS Orer, SM Barman - 2016 - researchgate.net
Comprised of the sympathetic nervous system, parasympathetic nervous system, and enteric
nervous system, the autonomic nervous system (ANS) provides the neural control of all parts …

Functional neuroanatomy of the central noradrenergic system

E Szabadi - Journal of psychopharmacology, 2013 - journals.sagepub.com
The central noradrenergic neurone, like the peripheral sympathetic neurone, is
characterized by a diffusely arborizing terminal axonal network. The central neurones …

The Concise Guide to PHARMACOLOGY 2013/14: G protein‐coupled receptors

SPH Alexander, HE Benson… - British journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Noradrenergic modulation of cognition: therapeutic implications

SR Chamberlain, TW Robbins - Journal of …, 2013 - journals.sagepub.com
The noradrenaline (norepinephrine) system exerts profound influences on cognition via
ascending projections to the forebrain, mostly originating from the locus coeruleus. This …

Functional organization of the sympathetic pathways controlling the pupil: light-inhibited and light-stimulated pathways

E Szabadi - Frontiers in Neurology, 2018 - frontiersin.org
Pupil dilation is mediated by a sympathetic output acting in opposition to
parasympathetically mediated pupil constriction. While light stimulates the parasympathetic …

Dexmedetomidine preconditioning may attenuate myocardial ischemia/reperfusion injury by down-regulating the HMGB1-TLR4-MyD88-NF-кB signaling pathway

J Zhang, K Peng, J Zhang, X Meng, F Ji - PLoS One, 2017 - journals.plos.org
Aims To investigate whether dexmedetomidine (DEX) preconditioning could alleviate the
inflammation caused by myocardial ischemia/reperfusion (I/R) injury by reducing HMGB1 …

Systemic dexmedetomidine augments inhibitory synaptic transmission in the superficial dorsal horn through activation of descending noradrenergic control: an in vivo …

Y Funai, AE Pickering, D Uta, K Nishikawa, T Mori… - PAIN®, 2014 - Elsevier
Abstract α 2-Adrenoceptors are widely distributed throughout the central nervous system
(CNS) and the systemic administration of α 2-agonists such as dexmedetomidine produces …

Polymorphic variants of adrenoceptors: pharmacology, physiology, and role in disease

A Ahles, S Engelhardt - Pharmacological reviews, 2014 - ASPET
The human genome encodes nine different adrenoceptor genes. These are grouped into
three families, namely, the α 1-, α 2-, and β-adrenoceptors, with three family members each …

Brimonidine tartrate for the treatment of glaucoma

DJ Oh, JL Chen, TS Vajaranant… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Brimonidine tartrate is a commonly used eyedrop for short-and long-term
lowering of intraocular pressure. Its use has been popularized due to its effects on aqueous …

[HTML][HTML] The search for novel analgesics: targets and mechanisms

TL Yaksh, SA Woller, R Ramachandran… - F1000prime …, 2015 - ncbi.nlm.nih.gov
The management of the pain state is of great therapeutic relevance to virtually every medical
specialty. Failure to manage its expression has deleterious consequence to the well-being …