Background Lung cancer is the second most common cancer and the leading cause of
cancer death for both men and women. Although low-dose CT (LDCT) is recommended for …

The majority of cancer-related deaths in the United States and worldwide are attributed to
lung cancer. There are more than 90 million smokers in the United States who represent a …

We have investigated the regulation of genes and associated molecular pathways, genome-
wide, in oral cells of electronic cigarette (e-cigs) users and cigarette smokers as compared to …

Abstract Objectives “PAULA's” test (P rotein A ssays U tilizing L ung cancer A nalytes) is a
novel multiplex immunoassay blood test that incorporates both tumor antigens and …

Background: Recent reports have shown that nuclear enriched abundant transcript 1
(NEAT1), a long noncoding RNA (lncRNA), contributes to the precise control of gene …

MiR-374a appears to play a complex role in non-small-cell lung cancer (NSCLC). Here, we
demonstrate a dual role for miR-374a in NSCLC pathogenesis. The effects and modulatory …

Lung cancer is the most common and lethal malignancy in the world. The landmark National
lung screening trial (NLST) showed a 20% relative reduction in mortality in high-risk …

A significant volume of research clearly shows that disease-related methylation changes can
be used as biomarkers at all stages of clinical disease management, including risk …

Background Vimentin is a member of the intermediate filament proteins and a canonical
marker of the epithelial-mesenchymal transition (EMT), which is pivotal in tumorigenesis …

Introduction Indeterminate pulmonary nodules (IPNs) lack clinical or radiographic features of
benign etiologies and often undergo invasive procedures unnecessarily, suggesting …