Ferroptosis in gastrointestinal cancer: from mechanisms to implications

R Zhang, R Kang, D Tang - Cancer Letters, 2023 - Elsevier
Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …

[HTML][HTML] Targeting serine-glycine-one-carbon metabolism as a vulnerability in cancers

W Sun, R Liu, X Gao, Z Lin, H Tang, H Cui, E Zhao - Biomarker Research, 2023 - Springer
The serine-glycine-one-carbon (SGOC) metabolic pathway is critical for DNA methylation,
histone methylation, and redox homeostasis, in addition to protein, lipid, and nucleotide …

Ferroptosis: Promising approach for cancer and cancer immunotherapy

S Zheng, XY Guan - Cancer Letters, 2023 - Elsevier
Ferroptosis is the cell death induced by ferrous ions and lipid peroxidation accumulation in
tumor cells. Targeting ferroptosis, which is regulated by various metabolic and immune …

[HTML][HTML] Crosstalk between ferroptosis and cuproptosis: From mechanism to potential clinical application

N Liu, M Chen - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Ferroptosis and cuproptosis, regulated forms of cell death resulting from metal ion
accumulation, are closely related in terms of occurrence, cell metabolism, signaling …

[HTML][HTML] Comprehensive analysis of cuproptosis-related lncRNAs for prognostic significance and immune microenvironment characterization in hepatocellular …

D Li, S Jin, P Chen, Y Zhang, Y Li, C Zhong… - Frontiers in …, 2023 - frontiersin.org
Cuproptosis was characterized as a novel type of programmed cell death. Recently,
however, the role of cuproptosis-related long noncoding RNAs (CRLs) in tumors has not yet …

[HTML][HTML] CD36-BATF2\MYB axis predicts anti-PD-1 immunotherapy response in gastric cancer

Q Jiang, Z Chen, F Meng, H Zhang… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Despite the utilization of anti-PD-1 therapy in gastric cancer (GC), the absence of a reliable
predictive biomarker continues to pose a challenge. In this study, we utilized bioinformatic …

LncRNA A2M-AS1 promotes ferroptosis in pancreatic cancer via interacting with PCBP3

X Qiu, Q Shi, X Zhang, X Shi, H Jiang, S Qin - Molecular Cancer Research, 2022 - AACR
Ferroptosis is a newly-discovered cell death mechanism involved in the progression of
various tumors, the role of noncoding RNAs (ncRNAs) in it was relatively less explored. This …

[HTML][HTML] Long non-coding RNA LOC339059 attenuates IL-6/STAT3-signaling-mediated PDL1 expression and macrophage M2 polarization by interacting with c-Myc in …

H Han, G Ding, S Wang, J Meng, Y Lv, W Yang… - Cancers, 2023 - mdpi.com
Simple Summary In this study, we analyzed the role of LOC339059 in PDL1 expression and
M2 polarization, which is mediated via the inhibition of IL-6/STAT3 signaling through …

Regulation of gut microbiota on immune cell ferroptosis: A novel insight for immunotherapy against tumor

R Liu, J Wang, Y Liu, Y Gao, R Yang - Cancer Letters, 2024 - Elsevier
Gut microbiota contributes to the homeostasis of immune system and is related to various
diseases such as tumorigenesis. Ferroptosis, a new type of cell death, is also involved in the …

[HTML][HTML] Integrated bioinformatics analysis of noncoding RNAs with tumor immune microenvironment in gastric cancer

J Xu, S Hu, Q Chen, L Shu, P Wang, J Wang - Scientific Reports, 2023 - nature.com
In recent years, molecular and genetic research hotspots of gastric cancer have been
investigated, including microRNAs, long noncoding RNAs (lncRNAs) and messenger RNA …