Drug consumption is driven by a drug's pharmacological effects, which are experienced as
rewarding, and is influenced by genetic, developmental, and psychosocial factors that …

Cigarette smoking is the single most important risk factor for the development of
cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has been in …

Brain endocannabinoid (eCB) signalling influences the motivation for natural rewards (such
as palatable food, sexual activity and social interaction) and modulates the rewarding effects …

Per-and polyfluoroalkyl substances (PFAS) are a group of persistent environmental
pollutants that are ubiquitously found in the environment and virtually in all living organisms …

Today tobacco use is the single greatest preventable cause of death in the world. Tobacco
use is often incorrectly perceived to be solely a personal choice. This is contradicted by the …

Tobacco products are products made of leaf tobacco and contain the highly addictive
ingredient, nicotine. Tobacco use is one of the main risk factors for cancer, cardiovascular …

The health risks of nicotine are well known, but there is some evidence of its beneficial
effects on cognitive function. The present review focused on the reported benefits of nicotine …

Substance use disorders (SUDs) remain a significant public health challenge, affecting tens
of millions of individuals worldwide each year. Often comorbid with other psychiatric …

Nicotine is a highly addictive compound present in tobacco, which causes the release of
dopamine in different regions of the brain. Recent studies have shown that astrocytes …

Addiction is a major public health problem with few efficacious and safe treatments. The goal
of this review is to provide an evidence-based assessment of the therapeutic role of the …