Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

T Kadowaki, T Yamauchi, N Kubota… - The Journal of …, 2006 - Am Soc Clin Investig
Adiponectin is an adipokine that is specifically and abundantly expressed in adipose tissue
and directly sensitizes the body to insulin. Hypoadiponectinemia, caused by interactions of …

Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies

S Shetty, CM Kusminski, PE Scherer - Trends in pharmacological sciences, 2009 - cell.com
Adiponectin is a secretory protein predominantly expressed by adipocytes and released at a
high rate into circulation. The ease with which the levels of adiponectin can be measured …

Metabolism regulator adiponectin prevents cardiac remodeling and ventricular arrhythmias via sympathetic modulation in a myocardial infarction model

Z Zhou, C Liu, S Xu, J Wang, F Guo, S Duan… - Basic Research in …, 2022 - Springer
The stellate ganglia play an important role in cardiac remodeling after myocardial infarction
(MI). This study aimed to investigate whether adiponectin (APN), an adipokine mainly …

[HTML][HTML] The usefulness of circulating adipokine levels for the assessment of obesity-related health problems

H Inadera - International journal of medical sciences, 2008 - ncbi.nlm.nih.gov
Because the prevalence of obesity has increased dramatically in recent years, one of the
key targets of public health is obesity and its associated pathological conditions. Obesity …

Adiponectin and mortality in patients undergoing coronary angiography

S Pilz, H Mangge, B Wellnitz, U Seelhorst… - The Journal of …, 2006 - academic.oup.com
Context: The adipokine adiponectin has been suggested to protect against coronary artery
disease (CAD). However, studies addressing the association between adiponectin and …

Adiponectin and arterial stiffness

A Mahmud, J Feely - American journal of hypertension, 2005 - academic.oup.com
Background: Adiponectin, an anti-inflammatory adipocytokine, is reduced in hypertension,
diabetes, and coronary artery disease (CAD). Arterial stiffness, as aortic pulse wave velocity …

Cardiac expression of adiponectin and its receptors in streptozotocin-induced diabetic rats

Z Guo, Z Xia, VG Yuen, JH McNeill - Metabolism, 2007 - Elsevier
Adiponectin can improve both glucose metabolism and insulin resistance via the adenosine
monophosphate–activated protein kinase (AMPK) signaling pathway. Activated AMPK …

Plasma adiponectin levels and clinical outcomes among haemodialysis patients

M Rao, L Li, H Tighiouart, BL Jaber… - Nephrology Dialysis …, 2008 - academic.oup.com
Background. Adiponectin (ADPN) levels are consistently elevated among patients with
advanced chronic kidney disease, but its relationship with cardiovascular outcomes in this …

Carbohydrate metabolism in uraemia

V Rigalleau, H Gin - Current Opinion in Clinical Nutrition & …, 2005 - journals.lww.com
The treatment of uraemia by renal replacement therapies or low-protein diets improves
insulin sensitivity. However, patients still have a high cardiovascular risk. The identification …

Plasma and urine levels of resistin and adiponectin in chronic kidney disease

S Yaturu, RD Reddy, J Rains, SK Jain - Cytokine, 2007 - Elsevier
Background: Subjects with chronic kidney disease (CKD) have an increased risk of
developing coronary atherosclerosis. Adipocyte hormones, resistin and adiponectin are …