[HTML][HTML] Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases

Z Kohandel, T Farkhondeh, M Aschner… - Biomedicine & …, 2022 - Elsevier
Astaxanthin (AST) is a red pigmented carotenoid with significant antioxidant, anti-
inflammatory, anti-proliferative, and anti-apoptotic properties. In this study, we summarize …

[HTML][HTML] Molecular and cellular pathways contributing to brain aging

A Zia, AM Pourbagher-Shahri, T Farkhondeh… - Behavioral and Brain …, 2021 - Springer
Aging is the leading risk factor for several age-associated diseases such as
neurodegenerative diseases. Understanding the biology of aging mechanisms is essential …

[HTML][HTML] Bax/Bcl-2 cascade is regulated by the EGFR pathway: therapeutic targeting of non-small cell lung cancer

M Alam, S Alam, A Shamsi, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR
is involved in several cancer developments, including NSCLC. The EGFR pathway …

[HTML][HTML] Thymoquinone, as a novel therapeutic candidate of cancers

B Almajali, HAN Al-Jamal, WRW Taib, I Ismail… - Pharmaceuticals, 2021 - mdpi.com
To date, natural products are widely used as pharmaceutical agents for many human
diseases and cancers. One of the most popular natural products that have been studied for …

A narrative review of the antitumor activity of monoterpenes from essential oils: An update

TQ Machado, ACC Da Fonseca… - BioMed research …, 2022 - Wiley Online Library
Monoterpenes are a group of natural products that have been widely studied due to their
therapeutic potential against various pathologies. These compounds are abundant in the …

[HTML][HTML] Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis

M Homayoonfal, Z Asemi, B Yousefi - Cellular & Molecular Biology Letters, 2022 - Springer
Despite great advances, therapeutic approaches of osteosarcoma, the most prevalent class
of preliminary pediatric bone tumors, as well as bone-related malignancies, continue to …

[HTML][HTML] RETRACTED: Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells

NA Alhakamy, SM Badr-Eldin, UA Fahmy, NK Alruwaili… - Pharmaceutics, 2020 - mdpi.com
Thymoquinone (TQ), a natural polyphenol, has been associated with various
pharmacological responses; however, low bioavailability of TQ limits its clinical application …

Therapeutic targeting of regulated signaling pathways of non-small cell lung carcinoma

GM Hasan, MI Hassan, SS Sohal, A Shamsi… - ACS omega, 2023 - ACS Publications
Non-small cell lung carcinoma (NSCLC) is the most common cancer globally.
Phytochemicals and small molecule inhibitors significantly prevent varying types of cancers …

Therapeutic implications and clinical manifestations of thymoquinone

M Alam, GM Hasan, MM Ansari, R Sharma, DK Yadav… - Phytochemistry, 2022 - Elsevier
Thymoquinone (TQ), a natural phytochemical predominantly found in Nigella sativa, has
been investigated for its numerous health benefits. TQ showed anti-cancer, anti-oxidant, and …

[HTML][HTML] Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and …

J Ansary, F Giampieri, TY Forbes-Hernandez, L Regolo… - Molecules, 2021 - mdpi.com
In recent times, scientific attention has been paid to different foods and their bioactive
components for the ability to inhibit the onset and progress of different types of cancer …