Increased ethanol intake after prenatal ethanol exposure: studies with animals

MG Chotro, C Arias, G Laviola - Neuroscience & Biobehavioral Reviews, 2007 - Elsevier
This review analyses the most relevant studies in which ethanol intake was measured after
prenatal exposure to the drug. Despite the variety in methodology, in most such studies this …

Assessing appetitive, aversive, and negative ethanol-mediated reinforcement through an immature rat model

RM Pautassi, ME Nizhnikov, NE Spear - Neuroscience & biobehavioral …, 2009 - Elsevier
The motivational effects of drugs play a key role during the transition from casual use to
abuse and dependence. Ethanol reinforcement has been successfully studied through …

[HTML][HTML] Prenatal alcohol exposure as a case of involuntary early onset of alcohol use: consequences and proposed mechanisms from animal studies

M Gaztañaga, A Angulo-Alcalde… - Frontiers in behavioral …, 2020 - frontiersin.org
Prenatal alcohol exposure has been found to be an important factor determining later
consumption of this drug. In humans, despite the considerable diversity of variables that …

Differential motivational properties of ethanol during early ontogeny as a function of dose and postadministration time

JC Molina, RM Pautassi, E Truxell, N Spear - Alcohol, 2007 - Elsevier
While appetitive reinforcement effects of ethanol are easily detected in rat neonates, such
phenomena rarely have been observed in older infants. Recently, Molina et al.[Molina, JC …

Fetal exposure to moderate ethanol doses: heightened operant responsiveness elicited by ethanol‐related reinforcers

SM March, P Abate, NE Spear… - Alcoholism: Clinical and …, 2009 - Wiley Online Library
Background: Prenatal exposure to moderate ethanol doses during late gestation modifies
postnatal ethanol palatability and ingestion. The use of Pavlovian associative procedures …

Acute sensitivity and acute tolerance to ethanol in preweanling rats with or without prenatal experience with the drug

C Arias, JC Molina, EC Mlewski, RM Pautassi… - Pharmacology …, 2008 - Elsevier
The present study examined behavioral sensitivity and acute tolerance to ethanol in infants
with or without a moderate prenatal ethanol experience. During gestational days 17–20 …

Participation of the endogenous opioid system in the acquisition of a prenatal ethanol-related memory: effects on neonatal and preweanling responsiveness to ethanol

RS Miranda-Morales, JC Molina, NE Spear… - Physiology & …, 2010 - Elsevier
The present study tested the involvement of the opioid system in the acquisition and
expression of prenatal ethanol-related memories. We evaluated how this prenatal …

Prenatal ethanol exposure increases ethanol reinforcement in neonatal rats

ME Nizhnikov, JC Molina… - Alcoholism: Clinical …, 2006 - Wiley Online Library
Background: Recent experimental findings indicate that newborn rats are quite susceptible
to the reinforcing properties of ethanol (EtOH). The basis seems to be more pharmacological …

Differential role of mu, delta and kappa opioid receptors in ethanol-mediated locomotor activation and ethanol intake in preweanling rats

C Arias, JC Molina, NE Spear - Physiology & behavior, 2010 - Elsevier
The opioid system modulates ethanol intake and reinforcement in adult and preweanling
rodents. While adult heterogeneous rats normally do not show ethanol-mediated locomotor …

Interactions between prenatal ethanol exposure and postnatal learning about ethanol in rat pups

C Arias, MG Chotro - Alcohol, 2006 - Elsevier
Exposure to ethanol during the last days of gestation (1 or 2/kg) has been shown to induce
greater ethanol intake as well as enhanced ethanol palatability in infant rats compared to …