Electrochemical sensing directions for next-generation healthcare: trends, challenges, and frontiers

JF Hernández-Rodríguez, D Rojas… - Analytical …, 2020 - ACS Publications
Unfortunately, last year we have witnessed one of the worst global health crises in recent
history. SARS-COV-2 pandemic outbreak has revealed that global healthcare systems were …

Regenerative approaches for chronic wounds

F Berthiaume, HC Hsia - Annual Review of Biomedical …, 2022 - annualreviews.org
Chronic skin wounds are commonly found in older individuals who have impaired circulation
due to diabetes or are immobilized due to physical disability. Chronic wounds pose a severe …

[HTML][HTML] Human-Based Advanced in vitro Approaches to Investigate Lung Fibrosis and Pulmonary Effects of COVID-19

M Kiener, N Roldan, C Machahua, A Sengupta… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic has caused considerable socio-
economic burden, which fueled the development of treatment strategies and vaccines at an …

Organ-on-a-chip: Current gaps and future directions

PL Candarlioglu, G Dal Negro, D Hughes… - Biochemical Society …, 2022 - portlandpress.com
As an emerging hot topic of the last decade, Organ on Chip (OoC) is a new technology that
is attracting interest from both basic and translational scientists. The Biochemical Society …

Oxygen measurement in microdevices

SM Grist, KL Bennewith… - Annual Review of …, 2022 - annualreviews.org
Oxygen plays a fundamental role in respiration and metabolism, and quantifying oxygen
levels is essential in many environmental, industrial, and research settings. Microdevices …

Tissue engineering approaches for the repair and regeneration of the anterior cruciate ligament: towards 3D bioprinted ACL-on-chip.

E Bakirci, OT Guenat, SS Ahmad… - European cells & …, 2022 - boris.unibe.ch
The anterior cruciate ligament (ACL) is the most frequently injured ligament in the knee. The
current method to treat the injured ligament is reconstruction using autografts and allografts …

[HTML][HTML] Immune cell extravasation in an organ-on-chip to model lung inflammation

L van Os, J Yeoh, G Witz, D Ferrari, P Krebs… - European Journal of …, 2023 - Elsevier
Acute respiratory distress syndrome (ARDS) is a severe lung condition with high mortality
and various causes, including lung infection. No specific treatment is currently available and …

[HTML][HTML] Development of Organs-on-Chips and Their Impact on Precision Medicine and Advanced System Simulation

Y Luo, X Li, Y Zhao, W Zhong, M Xing, G Lyu - Pharmaceutics, 2023 - mdpi.com
Drugs may undergo costly preclinical studies but still fail to demonstrate their efficacy in
clinical trials, which makes it challenging to discover new drugs. Both in vitro and in vivo …

[PDF][PDF] Effects of biomechanical and biochemical stimuli on angio-and vasculogenesis in a complex microvasculature-on-chip

D Ferrari, A Sengupta, L Heo, L Pethö, J Michler… - Iscience, 2023 - cell.com
The endothelium of blood vessels is a vital organ that reacts differently to subtle changes in
stiffness and mechanical forces exerted on its environment (extracellular matrix (ECM)) …

[HTML][HTML] Landscape of human organoids: Ideal model in clinics and research

X Han, C Cai, W Deng, Y Shi, L Li, C Wang… - The …, 2024 - ncbi.nlm.nih.gov
In the last decade, organoid research has entered a golden era, signifying a pivotal shift in
the biomedical landscape. The year 2023 marked a milestone with the publication of …