Role of microglia in diabetic neuropathic pain

Q Wang, Y Xie, S Ma, H Luo, Y Qiu - Frontiers in Cell and …, 2024 - frontiersin.org
Approximately one-third of the patients with diabetes worldwide suffer from neuropathic
pain, mainly categorized by spontaneous and stimulus-induced pain. Microglia are a class …

Electroacupuncture Alleviates Dry Eye Ocular Pain Through TNF-ɑ Mediated ERK1/2/P2X3R Signaling Pathway in SD Rats

MM Wan, T Jin, ZY Fu, SH Lai, WP Gao - Journal of Pain Research, 2023 - Taylor & Francis
Purpose This study aimed to examine electroacupuncture's influence on ocular pain and its
potential modulation of the TNF-ɑ mediated ERK1/2/P2X3R signaling pathway in dry eye …

Grape seed-derived procyanidins decreases neuropathic pain and nerve regeneration by suppression of toll-like receptor 4-myeloid differentiation factor-88 signaling

L Hu, E An, ZP Zhu, Y Cai, X Ye, H Zhou… - Molecular …, 2024 - journals.sagepub.com
Background: Recent studies have shown that peripheral nerve regeneration process is
closely related to neuropathic pain. Toll-like receptor 4 (TLR4) signaling was involved in …

Electroacupuncture Ameliorate Juvenile Collagen-Induced Arthritis by Regulating M1 Macrophages and Pyroptosis Signaling Pathways

F Khadour, YA Khadour, BM Ebrahem, J Liu, T Xu - 2023 - researchsquare.com
Background: Electroacupuncture (EA) exerts significant effects in clinic, such as anti-
inflammation, immune regulation, joint-related diseases, anti-cancer, etc. However, the …