Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …

Gene therapy represents a promising cancer treatment featuring high efficacy and limited
side effects, but it is stymied by a lack of safe and efficient gene-delivery vectors. Cationic …

Introduction: Nanoparticles have been successfully used for cancer drug delivery since
1995. In the design of commercial nanoparticles, size and surface characteristics have been …

Rapid emergence of antibiotic-resistant bacteria has made it harder for us to combat
infectious diseases and to develop new antibiotics. The clustered regularly interspaced short …

Nanomedicines afford unique advantages in therapeutic intervention against tumors.
However, conventional nanomedicines have failed to achieve the desired effect against …

There are an abundance of nanoparticle technologies being developed for use as part of
therapeutic strategies. This review focuses on a narrow class of metal nanoparticles that …

The cellular transport process of DNA is hampered by cell membrane barriers, and hence, a
delivery vehicle is essential for realizing the potential benefits of gene therapy to combat a …

Efficient gene therapy is mainly dependent on the gene transfer capability of gene delivery
vectors. Non-viral vectors have become the research interest of many researchers because …

Nowadays, gene delivery for therapeutic objects is considered one of the most promising
strategies to cure both the genetic and acquired diseases of human. The design of efficient …

The overuse of antibiotics plays a major role in the emergence and spread of multidrug-
resistant bacteria. A molecularly targeted, specific treatment method for bacterial pathogens …