High-efficiency dry powder aerosol delivery to children: Review and application of new technologies
While dry powder aerosol formulations offer a number of advantages, their use in children is
often limited due to poor lung delivery efficiency and difficulties with consistent dry powder …
often limited due to poor lung delivery efficiency and difficulties with consistent dry powder …
Advances in inhaled technologies: understanding the therapeutic challenge, predicting clinical performance, and designing the optimal inhaled product
P Bäckman, H Adelmann, G Petersson… - Clinical …, 2014 - Wiley Online Library
Inhaled medicines are designed mainly to provide safe and efficacious treatment of
respiratory diseases, offering the potential advantages of targeted drug delivery such as …
respiratory diseases, offering the potential advantages of targeted drug delivery such as …
[HTML][HTML] Perspective: Aerosol microphysics: From molecules to the chemical physics of aerosols
Aerosols are found in a wide diversity of contexts and applications, including the
atmosphere, pharmaceutics, and industry. Aerosols are dispersions of particles in a gas, and …
atmosphere, pharmaceutics, and industry. Aerosols are dispersions of particles in a gas, and …
Evaluation and modification of commercial dry powder inhalers for the aerosolization of a submicrometer excipient enhanced growth (EEG) formulation
The aim of this study was to evaluate and modify commercial dry powder inhalers (DPIs) for
the aerosolization of a submicrometer excipient enhanced growth (EEG) formulation. The …
the aerosolization of a submicrometer excipient enhanced growth (EEG) formulation. The …
The use of condensational growth methods for efficient drug delivery to the lungs during noninvasive ventilation high flow therapy
Purpose The objective of this study was to evaluate the delivery of nasally administered
aerosols to the lungs during noninvasive ventilation using controlled condensational growth …
aerosols to the lungs during noninvasive ventilation using controlled condensational growth …
Pulmonary aerosol delivery and the importance of growth dynamics
Aerosols are dynamic systems, responding to variations in the surrounding environmental
conditions by changing in size, composition and phase. Although, widely used in inhalation …
conditions by changing in size, composition and phase. Although, widely used in inhalation …
Dry powder formulation of kanamycin with enhanced aerosolization efficiency for drug-resistant tuberculosis
Background Kanamycin, an injectable agent, is currently used to treat drug-resistant
tuberculosis (TB). Parenteral kanamycin causes high systemic toxicity which could be …
tuberculosis (TB). Parenteral kanamycin causes high systemic toxicity which could be …
Development and characterization of nanoembedded microparticles for pulmonary delivery of antitubercular drugs against experimental tuberculosis
The foremost objective of the present research study was to develop and evaluate the
potential of rifampicin (RIF) and isoniazid (INH) loaded spray dried nanoembedded …
potential of rifampicin (RIF) and isoniazid (INH) loaded spray dried nanoembedded …
Regional deposition: targeting
AR Martin - Journal of aerosol medicine and pulmonary drug …, 2021 - liebertpub.com
Patterns of regional aerosol deposition within the lungs are known to vary in a predictable
manner with a number of factors, most notably aerodynamic particle size and inhalation …
manner with a number of factors, most notably aerodynamic particle size and inhalation …
High-efficiency generation and delivery of aerosols through nasal cannula during noninvasive ventilation
Background: Previous studies have demonstrated the delivery of pharmaceutical aerosols
through nasal cannula and the feasibility of enhanced condensational growth (ECG) with a …
through nasal cannula and the feasibility of enhanced condensational growth (ECG) with a …