High-efficiency dry powder inhalers (DPIs) were developed and tested for use with carrier-
free formulations across a range of different inhalation flow rates. Performance of a …

As pulmonary drug deposition is a function of aerosol particle size distribution, it is critical
that the dynamics of particle formation and maturation in pMDI sprays in the interim between …

Using the nasal route to deliver pharmaceutical aerosols to the lungs has a number of
advantages, including coadministration during noninvasive ventilation. The objective of this …

Background: Dry powder inhalers (DPIs) offer a number of advantages, such as rapid
delivery of high-dose inhaled medications; however, DPI use in children is often avoided …

Nasal delivery of lung targeted pharmaceutical aerosols is ideal for drugs that need to be
administered during high flow nasal cannula (HFNC) gas delivery, but based on previous …

Inline dry powder inhalers (DPIs) offer a potentially effective option to deliver high dose
inhaled medications simultaneously with mechanical ventilation. The objective of this study …

Background: An infant air-jet dry powder inhaler (DPI) platform has recently been developed
that in combination with highly dispersible spray-dried powder formulations can achieve …

Background: Nebulized aerosol drug delivery during the administration of noninvasive
positive pressure ventilation (NPPV) is commonly implemented. While studies have shown …

Purpose To demonstrate efficient aerosol delivery through an in vitro nasal model using a
dry powder inhaler (DPI) requiring low actuation air volumes (LV) applied during low-flow …

Inhaled aerosols have wide-ranging applications in the treatment and diagnosis of
respiratory diseases. Methacholine challenge testing (MCT) is a diagnostic test frequently …