To speculate on human responses from animal studies, scale-up factors (body weight, lung
volume, or lung surface area ratios) are currently used to extrapolate aerosol lung …

Currently, one-third of the world's population is infected with tuberculosis (TB) mainly spread
by inhalation of the tubercle bacilli, Mycobacterium tuberculosis. Patient non-compliance is …

The site of deposition of pulmonary delivered aerosols is dependent on the aerosol׳ s
droplet size distribution, which may change during inhalation. The aim of this study was to …

Nanoparticles have been widely employed as a drug delivery carrier and a direct targeting
agent. Off course, nanoparticles have been precisely and accurately designed to improve …

Background: In neonatal respiratory distress syndrome, breathing support and surfactant
therapy are commonly used to enable the alveoli to expand. Surfactants are typically …

Purpose In order to improve the delivery of dry powder aerosol formulations to the lungs of
infants, this study implemented an infant air-jet platform and explored the effects of different …

Background: Aerosol drug delivery to the lungs is known to be very inefficient during all
forms of noninvasive ventilation, especially when the aerosol is administered simultaneously …

Purpose To evaluate the efficiency of a new technique for delivering aerosols to intubated
infants that employs a new Y-connector, access port administration of a dry powder, and …

Purpose To predict the cellular-level epithelial absorbed dose from deposited inhaled
corticosteroid (ICS) particles in a model of an expanding and contracting small airway …

New active dry powder inhaler systems were developed and tested to efficiently aerosolize a
carrier-free formulation. To assess inhaler performance, a challenging case study of aerosol …