The factors that influence product development depend, amongst other things, on the type of
product, the economic situation, the state of the art technology and various social and …

Respiratory infections are a major cause of morbidity and mortality worldwide, particularly in
low-or middle-income countries. Direct drug delivery to the lungs is a promising approach for …

A major disadvantage of inhalation therapy with continuous drug delivery is the loss of
medication during expiration. Developing a breath-triggered drug release system can highly …

Pulmonary drug delivery is the preferred route of drug administration for many respiratory
diseases. Drug delivery devices like inhalers are convenient to use and can archive a …

Cystic Fibrosis (CF) is a degenerative disease, which causes thickening of the airway
surface liquid and reduced mucociliary clearance, which provides an ideal habitat for …

• Excipient Enhanced Growth (CFD)–Insulin+ Hygroscopic Excipient.• Moving to< 1 μm
particles, reduced mouth-throat deposition by one order of magnitude to< 1% of drug dose.• …

Background: An inhaled formulation of azithromycin (AZ) may be advantageous for the local
treatment of pulmonary infections and associated inflammation without causing the systemic …

SUMMARY Background: Current DPIs on the market have fine particle fractions (FPF) in the
range of 10-70%, produce high mouth-throat (MT) depositional losses of approximately 30 …