Iron overload cardiomyopathy (IOC) is a major cause of death in patients with diseases
associated with chronic anemia such as thalassemia or sickle cell disease after chronic …

Although iron is a metal involved in many vital processes due to its redox capacity, body iron
overloads lead to tissue damage, including the cardiovascular system. While …

Aims We previously demonstrated that iron overload induces endothelial dysfunction and
oxidative stress, which could increase the risk for atherosclerosis. However, the iron-related …

Neuroinflammation plays a crucial role in the occurrence and development of cognitive
impairment in type 2 diabetes mellitus (T2DM), but the specific injury mechanism is not fully …

Ferroptosis is a recently identified cell death characterized by an excessive accumulation of
iron-dependent reactive oxygen species (ROS) and lipid peroxides. Intracellular iron …

Ethnopharmacological relevance Atherosclerosis (AS) is a chronic vascular ailment
characterized by inflammatory and lipid deposition in the arterial wall caused by endothelial …

Abstract α-Synuclein plays a central role in synucleinopathies pathogenesis such as
Parkinson's disease (PD). Phosphorylation is the most common and important protein …

The role of hepcidin in iron homeostasis in preeclamptic pregnant women is unclear. To test
the hypothesis that increased serum iron in women diagnosed with preeclampsia results …

Significance: Hydrogen sulfide (H2S) is an endogenous signaling molecule, regulating
numerous physiological functions from vasorelaxation to neuromodulation. Iron is a well …

Abstract Purpose of Review To discuss the physiologic and pathologic effects of iron on
men's reproductive health. Recent Findings Iron overload diseases are associated with …