[HTML][HTML] Inflammation-mediated tissue damage in pulmonary tuberculosis and host-directed therapeutic strategies

D Tiwari, AR Martineau - Seminars in Immunology, 2023 - Elsevier
Abstract Treatment of tuberculosis (TB) involves the administration of anti-mycobacterial
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …

Pathology of TB/COVID-19 co-infection: the phantom menace

GT Mousquer, A Peres, M Fiegenbaum - Tuberculosis, 2021 - Elsevier
Tuberculosis (TB) and coronavirus disease 2019 (COVID-19) are currently the two main
causes of death among infectious diseases. There is an increasing number of studies trying …

[HTML][HTML] Corticosteroids for COVID-19 therapy: potential implications on tuberculosis

R Gopalaswamy, S Subbian - International journal of molecular sciences, 2021 - mdpi.com
On 11 March 2020, the World Health Organization announced the Corona Virus Disease-
2019 (COVID-19) as a global pandemic, which originated in China. At the host level, COVID …

[HTML][HTML] Neutrophils in tuberculosis-associated inflammation and lung pathology

CN Muefong, JS Sutherland - Frontiers in immunology, 2020 - frontiersin.org
Protective immunity to Mycobacterium tuberculosis (Mtb)—the causative agent of
tuberculosis (TB)—is not fully understood but involves immune responses within the …

[HTML][HTML] Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit

JA Brown, SG Codreanu, M Shi, SD Sherrod… - Journal of …, 2016 - Springer
Background Understanding blood-brain barrier responses to inflammatory stimulation (such
as lipopolysaccharide mimicking a systemic infection or a cytokine cocktail that could be the …

[HTML][HTML] Macrophage metabolic reprogramming during chronic lung disease

PP Ogger, AJ Byrne - Mucosal immunology, 2021 - Elsevier
Airway macrophages (AMs) play key roles in the maintenance of lung immune tolerance.
Tissue tailored, highly specialised and strategically positioned, AMs are critical sentinels of …

[HTML][HTML] Malnutrition: modulator of immune responses in tuberculosis

P Chandrasekaran, N Saravanan… - Frontiers in …, 2017 - frontiersin.org
Nutrition plays a major role in the management of both acute and chronic diseases, in terms
of body's response to the pathogenic organism. An array of nutrients like macro-and micro …

Superinfection with SARS-CoV-2 has deleterious effects on mycobacterium bovis BCG immunity and promotes dissemination of mycobacterium tuberculosis

RE Hildebrand, SS Chandrasekar, M Riel… - Microbiology …, 2022 - Am Soc Microbiol
An estimated one-third of the world's population is infected with Mycobacterium tuberculosis,
with the majority being vaccinated with Mycobacterium bovis BCG. Severe acute respiratory …

[HTML][HTML] The relationship between previous pulmonary tuberculosis and risk of lung cancer in the future

Y Qin, Y Chen, J Chen, K Xu, F Xu, J Shi - Infectious Agents and Cancer, 2022 - Springer
Various investigations have expanded the views that tuberculosis is an important risk factor
for lung cancer occurrence. Lung cancer originates from chronic inflammation and infection …

[HTML][HTML] Pathogenesis of SARS-CoV-2 and Mycobacterium tuberculosis Coinfection

T Shah, Z Shah, N Yasmeen, Z Baloch… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease-2019 (COVID-19), caused by SARS-CoV-2, is an infectious disease
that poses severe threats to global public health and significant economic losses. The …