High-density lipoprotein revisited: biological functions and clinical relevance

A von Eckardstein, BG Nordestgaard… - European heart …, 2023 - academic.oup.com
Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …

High-density lipoproteins, reverse cholesterol transport and atherogenesis

HJ Pownall, C Rosales, BK Gillard… - Nature Reviews …, 2021 - nature.com
Plasma HDL-cholesterol concentrations correlate negatively with the risk of atherosclerotic
cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its …

[HTML][HTML] High-dimensional characterization of post-acute sequelae of COVID-19

Z Al-Aly, Y Xie, B Bowe - Nature, 2021 - nature.com
The acute clinical manifestations of COVID-19 have been well characterized,, but the post-
acute sequelae of this disease have not been comprehensively described. Here we use the …

[HTML][HTML] Burdens of post-acute sequelae of COVID-19 by severity of acute infection, demographics and health status

Y Xie, B Bowe, Z Al-Aly - Nature communications, 2021 - nature.com
Abstract The Post-Acute Sequelae of SARS-CoV-2 infection (PASC) have been
characterized; however, the burden of PASC remains unknown. Here we used the …

[HTML][HTML] Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016

Y Xie, B Bowe, AH Mokdad, H Xian, Y Yan, T Li… - Kidney international, 2018 - Elsevier
The last quarter century witnessed significant population growth, aging, and major changes
in epidemiologic trends, which may have shaped the state of chronic kidney disease (CKD) …

Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies

CM Madsen, A Varbo… - European heart …, 2017 - academic.oup.com
Aims High-density lipoprotein (HDL) cholesterol concentrations are inversely associated
with cardiovascular disease and mortality across a range of concentrations, but genetic …

High HDL (high-density lipoprotein) cholesterol increases cardiovascular risk in hypertensive patients

V Trimarco, R Izzo, C Morisco, P Mone… - …, 2022 - Am Heart Assoc
Background: Emerging evidence suggests that elevated circulating levels of HDL-C (high-
density lipoprotein cholesterol) could be linked to an increased mortality risk. However, to …

Burden of cause-specific mortality associated with PM2. 5 air pollution in the United States

B Bowe, Y Xie, Y Yan, Z Al-Aly - JAMA network open, 2019 - jamanetwork.com
Importance Ambient fine particulate matter (PM 2.5) air pollution is associated with
increased risk of several causes of death. However, epidemiologic evidence suggests that …

[HTML][HTML] Particulate matter air pollution and the risk of incident CKD and progression to ESRD

B Bowe, Y Xie, T Li, Y Yan, H Xian… - Journal of the American …, 2018 - journals.lww.com
Elevated levels of fine particulate matter< 2.5 µm in aerodynamic diameter (PM 2.5) are
associated with increased risk of cardiovascular outcomes and death, but their association …

[HTML][HTML] HDL cholesterol: reappraisal of its clinical relevance

W März, ME Kleber, H Scharnagl, T Speer… - Clinical Research in …, 2017 - Springer
Background While several lines of evidence prove that elevated concentrations of low-
density lipoproteins (LDL) causally contribute to the development of atherosclerosis and its …