Fibrosis, which is characterized by excessive extracellular matrix (ECM) deposition, is a
wound-healing response to organ injury and may promote cancer and failure in various …

Cervical cancer (CC) is an important public health problem for women, and perspectives
and information regarding its prevention and treatment are quickly evolving. Human …

Background Ginkgo biloba L., a kind of traditional Chinese medicine, is always used to treat
various diseases. Ginkgetin is an active biflavonoid isolated from leaves of Ginkgo biloba L …

Gynecological and breast tumors are one of the main causes of cancer-related mortalities
among women. Despite recent advances in diagnostic and therapeutic methods, tumor …

Background Malignant cells may arise from dedifferentiation of mature cells and acquire
features of the progenitor cells. Definitive endoderm from which liver is derived, expresses …

Recent studies have shown that autophagy plays an important role in gynecologic tumors,
and ubiquitin modification of autophagy regulatory components is essential to regulate …

Malignant ovarian tumors bear the highest mortality rate among all gynecological cancers.
Both late tumor diagnosis and tolerance to available chemotherapy increase patient …

Background: Nicotinamide adenine dinucleotide (NAD+) has emerged as a critical regulator
of cell signaling and survival pathways, affecting tumor initiation and progression. In this …

沉默SIRT1降低胆管癌细胞对5-氟尿嘧啶的耐药：基于抑制FOXO1/Rab7自噬通路- PMC Back
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Sirtuins (SIRTs) belong to the family of nicotine adenine dinucleotide (NAD+)-dependent
class III histone deacetylases, which come into play in the regulation of epigenetic …