Innate Immunity against Cryptococcus, from Recognition to Elimination

A Campuzano, FL Wormley Jr - Journal of fungi, 2018 - mdpi.com
Cryptococcus species, the etiological agents of cryptococcosis, are encapsulated fungal
yeasts that predominantly cause disease in immunocompromised individuals, and are …

Immunology of cryptococcal infections: developing a rational approach to patient therapy

W Elsegeiny, KA Marr, PR Williamson - Frontiers in immunology, 2018 - frontiersin.org
Cryptococcal meningoencephalitis is responsible for upwards of 15% of HIV-related deaths
worldwide and is currently the most common cause of non-viral meningitis in the US …

High‐throughput sequencing identifies aetiology‐dependent differences in ductular reaction in human chronic liver disease

O Govaere, S Cockell, M Van Haele… - The Journal of …, 2019 - Wiley Online Library
Ductular reaction (DR) represents the activation of hepatic progenitor cells (HPCs) and has
been associated with features of advanced chronic liver disease; yet it is not clear whether …

A novel CD206 targeting peptide inhibits bleomycin-induced pulmonary fibrosis in mice

A Ghebremedhin, AB Salam, B Adu-Addai, S Noonan… - Cells, 2023 - mdpi.com
Activated M2-polarized macrophages are drivers of pulmonary fibrosis in several clinical
scenarios, including Idiopathic Pulmonary Fibrosis (IPF). In this study, we investigated the …

TNF-α-Producing Cryptococcus neoformans Exerts Protective Effects on Host Defenses in Murine Pulmonary Cryptococcosis

Z Fa, J Xu, J Yi, J Sang, W Pan, Q Xie, R Yang… - Frontiers in …, 2019 - frontiersin.org
Tumor necrosis factor alpha (TNF-α) plays a critical role in the control of cryptococcal
infection, and its insufficiency promotes cryptococcal persistence. To explore the therapeutic …

Dendritic Cells: Multifunctional Roles in Host Defenses to Cryptococcus Infections

KD Goughenour, AS Nair, J Xu, MA Olszewski… - Journal of Fungi, 2023 - mdpi.com
Fungal infections are an increasingly growing public health concern, and Cryptococcus is
one of the most problematic fungal organisms causing substantial mortality and morbidity …

Role of a macrophage receptor with collagenous structure (MARCO) in regulating monocyte/macrophage functions in ayu, Plecoglossus altivelis

L Zhang, L Nie, SY Cai, J Chen, J Chen - Fish & shellfish immunology, 2018 - Elsevier
Macrophage receptor with collagenous structure (MARCO) plays essential roles in
phagocytic cell-mediated innate immune responses. However, studies regarding MARCO …

Cryptococcus gattii polysaccharide capsule: An insight on fungal‐host interactions and vaccine studies

GJC Freitas, DA Santos - European Journal of Immunology, 2021 - Wiley Online Library
Cryptococcus neoformans and C. gattii complexes are the main causative agents of
cryptococcosis, a neglected disease with high lethality. The capsule, composed …

The application of MARCO for immune regulation and treatment

G Zhou, L Zhang, S Shao - Molecular Biology Reports, 2024 - Springer
Macrophage receptor with collagen structure (MARCO) is a member of scavenger receptor
class A (SR-A) and shares structural and functional similarities with SR-A1. In recent years …

Monocytes contribute to a pro‐healing response in 40 μm diameter uniform‐pore, precision‐templated scaffolds

NR Chan, B Hwang, BD Ratner… - Journal of tissue …, 2022 - Wiley Online Library
Porous precision‐templated scaffolds (PTS) with uniformly distributed 40 μm spherical pores
have shown a remarkable ability in immunomodulating resident cells for tissue regeneration …