Kinases are key regulatory signalling proteins governing numerous essential biological
processes and cellular functions. Dysregulation of many protein kinases is associated with …

Colorectal cancer (CRC) represents one of the most common cancers worldwide, with a
high mortality rate despite the decreasing incidence and new diagnostic and therapeutic …

In recent decades, the development of targeted drugs has featured prominently in the
treatment of cancer, which is among the major causes of mortality globally. Triazole-fused …

Here, a novel approach is presented to improve the efficacy of antibody‐drug conjugates
(ADC) by integrating antibody‐mediated immunotherapy and photodynamic therapy (PDT) …

Abstract Zinc finger protein 671 (ZNF671) has been described as a vital cancer inhibitor in
multiple neoplasms, yet the functional roles of ZNF671 in colorectal carcinoma (CRC) …

Colorectal cancer is among the most prevalent and lethal cancers globally. To address this
emergency, countries have developed diffuse screening programs and innovative surgical …

During the last few decades, the treatment options available for patients with metastatic
colorectal cancer (mCRC) have undergone continuous improvements, transitioning from …

Se identificó el fármaco etopósido, del que se evalúan las propiedades farmacocinéticas y
de toxicidad mediante predicciones bioinformáticas utilizando modelos QSAR VEGA y …

Цель. Оценка уровня TGF-β1 в сыворотке крови, ткани опухоли и лимфатических узлов
у пациентов с новообразованиями толстого кишечника. Материалы и методы …

Цель. Оценка уровня TGF-β1 в сыворотке крови, ткани опухоли и лимфатических узлов
у пациентов с новообразованиями толстого кишечника. Материалы и методы …