A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …
Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years
The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
Updating Phospholipase A2 Biology
M Murakami, H Sato, Y Taketomi - Biomolecules, 2020 - mdpi.com
The phospholipase A2 (PLA2) superfamily contains more than 50 enzymes in mammals that
are subdivided into several distinct families on a structural and biochemical basis. In …
are subdivided into several distinct families on a structural and biochemical basis. In …
Peroxisome proliferator-activated receptors: Experimental targeting for the treatment of inflammatory bowel diseases
J Decara, P Rivera, AJ López-Gambero… - Frontiers in …, 2020 - frontiersin.org
The peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor
proteins that promote ligand-dependent transcription of target genes that regulate energy …
proteins that promote ligand-dependent transcription of target genes that regulate energy …
Fecal metabolomic signatures in colorectal adenoma patients are associated with gut microbiota and early events of colorectal cancer pathogenesis
Colorectal adenomas are precancerous lesions of colorectal cancer (CRC) that offer a
means of viewing the events key to early CRC development. A number of studies have …
means of viewing the events key to early CRC development. A number of studies have …
Oxidative stress and lipid mediators modulate immune cell functions in autoimmune diseases
P Wójcik, A Gęgotek, N Žarković… - International journal of …, 2021 - mdpi.com
Autoimmune diseases, including psoriasis, systemic lupus erythematosus (SLE), and
rheumatic arthritis (RA), are caused by a combination of environmental and genetic factors …
rheumatic arthritis (RA), are caused by a combination of environmental and genetic factors …
Endocannabinoid system as a promising therapeutic target in inflammatory bowel disease–a systematic review
S Hryhorowicz, M Kaczmarek-Ryś, A Zielińska… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is a general term used to describe a group of chronic
inflammatory conditions of the gastrointestinal tract of unknown etiology, including two …
inflammatory conditions of the gastrointestinal tract of unknown etiology, including two …
Cannabinoids as anticancer therapeutic agents
O Kovalchuk, I Kovalchuk - Cell Cycle, 2020 - Taylor & Francis
The recent announcement of marijuana legalization in Canada spiked many discussions
about potential health benefits of Cannabis sativa. Cannabinoids are active chemical …
about potential health benefits of Cannabis sativa. Cannabinoids are active chemical …
Endocannabinoids, cannabinoids and the regulation of anxiety
Cannabis has been used for hundreds of years, with its ability to dampen feelings of anxiety
often reported as a primary reason for use. Only recently has the specific role cannabinoids …
often reported as a primary reason for use. Only recently has the specific role cannabinoids …