The prevalence of chronic kidney disease (CKD) is increasing worldwide, and the mortality
rate continues to be unacceptably high. The biomarkers currently used in clinical practice …

Chronic kidney disease (CKD) has been recognized as a global public health problem.
Despite the current advances in medicine, CKD-associated morbidity and mortality remain …

Diabetic nephropathy (DN) is a primary cause of end‑stage renal disease. Despite the
beneficial effects of astragaloside IV (AS)‑IV on renal disease, the underlying mechanism of …

Osteopontin (OPN) is a ubiquitously expressed protein with a wide range of physiological
functions, including roles in bone mineralization, immune regulation, and wound healing …

Diabetic kidney disease (DKD), accompanied by chronic low-grade inflammation, is one of
the most common complications of diabetes. Armillariella tabescens has potent anti …

High Tumor Necrosis Factor Receptor 2 (TNFR2) expression is characteristic of diverse
malignant cells during tumorigenesis. The protein is also expressed by many …

Aim of the present study was to investigate the possible involvement of TNF-α signaling
pathway and T-lymphocyte activation in DN. Eighty-two diabetic patients [39 male, age 69.5 …

Rationale & Objective The effects of acute kidney injury (AKI) on long-term kidney function,
cardiovascular disease, and mortality are well documented. We aimed to identify biomarkers …

Renal fibrosis is the final common pathophysiological pathway in chronic kidney disease
(CKD) regardless of the underlying cause of kidney injury. Tubulointerstitial fibrosis (TIF) is …

Diabetes mellitus is the leading cause of chronic kidney disease, and about 30–40% of
patients with diabetes will develop kidney disease. Incretin hormones have received …