2016 AHA/ACC guideline on the management of patients with lower extremity peripheral artery disease: a report of the American College of Cardiology/American …

MD Gerhard-Herman, HL Gornik, C Barrett… - Journal of the American …, 2017 - jacc.org
The recommendations listed in this guideline are, whenever possible, evidence based. An
initial extensive evidence review, which included literature derived from research involving …

The role of phosphorus in the development and progression of vascular calcification

J Kendrick, M Chonchol - American Journal of Kidney Diseases, 2011 - Elsevier
Vascular calcification is associated with significant cardiovascular morbidity and mortality in
patients with chronic kidney disease (CKD). Factors unique to patients with CKD, such as …

Magnesium reduces calcification in bovine vascular smooth muscle cells in a dose-dependent manner

F Kircelli, ME Peter, E Sevinc Ok… - Nephrology Dialysis …, 2012 - academic.oup.com
Abstract Background. Vascular calcification (VC), mainly due to elevated phosphate levels,
is one major problem in patients suffering from chronic kidney disease. In clinical studies, an …

Urea, a true uremic toxin: the empire strikes back

WL Lau, ND Vaziri - Clinical Science, 2017 - portlandpress.com
Blood levels of urea rise with progressive decline in kidney function. Older studies
examining acute urea infusion suggested that urea was well-tolerated at levels 8–10× above …

Role of uremic toxin indoxyl sulfate in the progression of cardiovascular disease

H Gao, S Liu - Life sciences, 2017 - Elsevier
The prevalence of cardiovascular disease (CVD) among patients with chronic kidney
disease (CKD) is relatively high. Deterioration of renal function in CKD leads to …

Bone alkaline phosphatase in CKD–mineral bone disorder

S Sardiwal, P Magnusson, DJA Goldsmith… - American journal of …, 2013 - Elsevier
Overall and cardiovascular mortality in patients with chronic kidney disease (CKD) is greatly
increased, without obvious current effective treatments. Mineral and bone disorder (MBD) is …

Vascular calcification in end‐stage renal disease

KL Jablonski, M Chonchol - Hemodialysis International, 2013 - Wiley Online Library
Vascular calcification is highly prevalent in end‐stage renal disease and independently
predictive of future cardiovascular events and mortality. C alcification can occur in both the …

[HTML][HTML] Vascular calcification in chronic kidney disease is induced by bone morphogenetic protein-2 via a mechanism involving the Wnt/β-catenin pathway

S Rong, X Zhao, X Jin, Z Zhang, L Chen… - Cellular Physiology and …, 2014 - karger.com
Background: Vascular calcification (VC), in which vascular smooth muscle cells (VSMCs)
undergo a phenotypic transformation into osteoblast-like cells, is one of the emergent risk …

Risk factors for progression of coronary artery calcification in patients with chronic kidney disease: the CRIC study

JD Bundy, J Chen, W Yang, M Budoff, AS Go… - Atherosclerosis, 2018 - Elsevier
Background and aims Coronary artery calcification (CAC) is common among patients with
chronic kidney disease (CKD) and predicts the risk for cardiovascular disease (CVD). We …

Benefits of regular walking exercise in advanced pre-dialysis chronic kidney disease

GC Kosmadakis, SG John, EL Clapp… - Nephrology dialysis …, 2012 - academic.oup.com
Background. There is increasing evidence of the benefit of regular physical exercise in a
number of long-term conditions including chronic kidney disease (CKD). In CKD, this …