[HTML][HTML] Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to …

JM Oh, BC Ahn - Theranostics, 2021 - ncbi.nlm.nih.gov
The advanced, metastatic differentiated thyroid cancers (DTCs) have a poor prognosis
mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of …

Transcription factor NF-κB: an update on intervention strategies

A Panday, ME Inda, P Bagam, MK Sahoo… - Archivum immunologiae …, 2016 - Springer
The nuclear factor (NF)-κB family of transcription factors are ubiquitous and pleiotropic
molecules that regulate the expression of more than 150 genes involved in a broad range of …

Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features

JM Dolezal, A Trzcinska, CY Liao, S Kochanny… - Modern …, 2021 - nature.com
Noninvasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP) are
follicular-patterned thyroid neoplasms defined by nuclear atypia and indolent behavior. They …

The RET oncogene in papillary thyroid carcinoma

JD Prescott, MA Zeiger - Cancer, 2015 - Wiley Online Library
Papillary thyroid carcinoma (PTC) is the most common form of thyroid cancer, accounting for
greater than 80% of cases. Surgical resection, with or without postoperative radioiodine …

New insights in thyroid cancer and p53 family proteins

L Manzella, S Stella, MS Pennisi, E Tirrò… - International journal of …, 2017 - mdpi.com
Thyroid cancers are common endocrine malignancies that comprise tumors with different
clinical and histological features. Indeed, papillary and follicular thyroid cancers are slow …

Chemotherapy and chemoprevention by thiazolidinediones

E Fröhlich, R Wahl - BioMed research international, 2015 - Wiley Online Library
Thiazolidinediones (TZDs) are synthetic ligands of Peroxisome‐Proliferator‐Activated
Receptor gamma (PPARγ). Troglitazone, rosiglitazone, and pioglitazone have been …

Genome-wide analysis of long noncoding RNA expression profile in papillary thyroid carcinoma

X Lan, H Zhang, Z Wang, W Dong, W Sun, L Shao… - Gene, 2015 - Elsevier
Long noncoding RNAs (lncRNAs) have been proved to play important roles in cancer
biology. To understand their expression profile and potential functions in papillary thyroid …

Plasma lipidomics profiling reveals biomarkers for papillary thyroid cancer diagnosis

N Jiang, Z Zhang, X Chen, G Zhang, Y Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
The objective of this study was to identify potential biomarkers and possible metabolic
pathways of malignant and benign thyroid nodules through lipidomics study. A total of 47 …

Diversity of mutations in the RET proto-oncogene and its oncogenic mechanism in medullary thyroid cancer

M Hedayati, M Zarif Yeganeh… - Critical reviews in …, 2016 - Taylor & Francis
Thyroid cancer is the most common endocrine malignancy and accounts for nearly 1% of all
of human cancer. Thyroid cancer has four main histological types: papillary, follicular …

Inhibition of BRD4 suppresses tumor growth and enhances iodine uptake in thyroid cancer

X Gao, X Wu, X Zhang, W Hua, Y Zhang… - Biochemical and …, 2016 - Elsevier
Thyroid cancer is a common malignancy of the endocrine system. Although radioiodine 131
I treatment on differentiated thyroid cancer is widely used, many patients still fail to benefit …