Covering: 2000 to 2013 Oxidative stress is the central component of chronic diseases. The
nuclear factor erythroid 2-related factor 2/antioxidant response element (Nrf2/ARE) pathway …

Vitamin D system comprises hormone precursors, active metabolites, carriers, enzymes, and
receptors involved in genomic and non-genomic effects. In addition to classical bone-related …

Well-established studies have shown an elevated level of reactive oxygen species (ROS)
that induces oxidative stress in the Alzheimer's disease (AD) patient's brain and an animal …

The top-down approach to proteomics offers compelling advantages due to the potential to
provide complete characterization of protein sequence and post-translational modifications …

Free radicals can be generated in a wide variety of chemical and biological systems,
including the formation of plastics, the ageing of paints, the combustion of fuels and in the …

Increasing evidence demonstrates that β-amyloid (Aβ) elicits oxidative stress, which
contributes to the pathogenesis and disease progression of Alzheimer's disease (AD). The …

Iron species can participate in the Fenton or Fenton‐like reaction to generate oxidizing
species that can cause oxidative damages to biomolecules and induce oxidative stress in …

The initiation and progression of Alzheimer disease (AD) is a complex process not yet fully
understood. While many hypotheses have been provided as to the cause of the disease, the …

Glutathione (GSH) is the major non-protein thiol in humans and other mammals, which is
present in millimolar concentrations within cells, but at much lower concentrations in the …

Mitochondria are important for providing cellular energy ATP through the oxidative
phosphorylation pathway. They are also critical in regulating many cellular functions …