Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Nanoparticles in drug delivery: From history to therapeutic applications
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …
Advances in our understanding of the molecular mechanisms of action of cisplatin in cancer therapy
PB Tchounwou, S Dasari, FK Noubissi… - Journal of …, 2021 - Taylor & Francis
Cisplatin and other platinum-based chemotherapeutic drugs have been used extensively for
the treatment of human cancers such as bladder, blood, breast, cervical, esophageal, head …
the treatment of human cancers such as bladder, blood, breast, cervical, esophageal, head …
Recent advances in active targeting of nanomaterials for anticancer drug delivery
One of the challenges in cancer chemotherapy is the low target to non-target ratio of
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
Association of the epithelial–mesenchymal transition (EMT) with cisplatin resistance
M Ashrafizadeh, A Zarrabi, K Hushmandi… - International journal of …, 2020 - mdpi.com
Therapy resistance is a characteristic of cancer cells that significantly reduces the
effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent …
effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent …
Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases
S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …
Applications and strategies in nanodiagnosis and nanotherapy in lung cancer
Lung cancer is the second most common cancer and the leading cause of death in both men
and women in the world. Lung cancer is heterogeneous in nature and diagnosis is often at …
and women in the world. Lung cancer is heterogeneous in nature and diagnosis is often at …
Utilization of polymer-lipid hybrid nanoparticles for targeted anti-cancer therapy
Cancer represents one of the most dangerous diseases, with 1.8 million deaths worldwide.
Despite remarkable advances in conventional therapies, these treatments are not effective …
Despite remarkable advances in conventional therapies, these treatments are not effective …
Triple negative breast cancer and non-small cell lung cancer: Clinical challenges and nano-formulation approaches
Triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC) are amongst
the most aggressive forms of solid tumors. TNBC is highlighted by absence of genetic …
the most aggressive forms of solid tumors. TNBC is highlighted by absence of genetic …