[HTML][HTML] Lymph node metastasis in cancer progression: molecular mechanisms, clinical significance and therapeutic interventions

H Ji, C Hu, X Yang, Y Liu, G Ji, S Ge, X Wang… - … and Targeted Therapy, 2023 - nature.com
Lymph nodes (LNs) are important hubs for metastatic cell arrest and growth, immune
modulation, and secondary dissemination to distant sites through a series of mechanisms …

Thyroid carcinoma, version 2.2022, NCCN clinical practice guidelines in oncology

RI Haddad, L Bischoff, D Ball, V Bernet… - Journal of the National …, 2022 - jnccn.org
Differentiated thyroid carcinomas is associated with an excellent prognosis. The treatment of
choice for differentiated thyroid carcinoma is surgery, followed by radioactive iodine ablation …

Prophylactic central neck dissection for clinically node‐negative papillary thyroid carcinoma

KM Alsubaie, HM Alsubaie, FR Alzahrani… - The …, 2022 - Wiley Online Library
Objective We performed a systematic review and meta‐analysis of randomized controlled
trials (RCTs) that scrutinized the oncological benefits and postsurgical complications of total …

A prospective randomized controlled trial to assess the efficacy and safety of prophylactic central compartment lymph node dissection in papillary thyroid carcinoma

J Ahn, JH Kwak, SG Yoon, JW Yi, HW Yu, H Kwon… - Surgery, 2022 - Elsevier
Background The efficacy of prophylactic central compartment lymph node dissection for
papillary thyroid carcinoma remains controversial. We performed a randomized controlled …

Lymph node yield in the initial central neck dissection (CND) associated with the risk of recurrence in papillary thyroid cancer: A reoperative CND cohort study

ST Yu, JN Ge, BH Sun, ZG Wei, ZZ Xiao, ZC Zhang… - Oral Oncology, 2021 - Elsevier
Background To evaluate the relationship between lymph node yield (LNY) from the initial
central neck dissection (CND) and the risk of recurrence in patients undergoing reoperative …

[HTML][HTML] Impact of lymph node dissection on postoperative complications of total thyroidectomy in patients with thyroid carcinoma

G Baud, A Jannin, C Marciniak, B Chevalier, C Do Cao… - Cancers, 2022 - mdpi.com
Simple Summary Thyroid cancers are the most common endocrine cancers and their
incidence has increased significantly in recent decades worldwide. Total thyroidectomy is …

Prophylactic central neck lymph node dissection in low-risk thyroid carcinoma patients does not decrease the incidence of locoregional recurrence: a meta-analysis of …

A Sanabria, C Betancourt-Agüero… - Annals of …, 2022 - journals.lww.com
Objective: To evaluate the effectiveness of T+ prophylactic CND (T+ CND) compared to T
alone on locoregional recurrence in patients with PTC. Summary background data: Few …

[HTML][HTML] An integrated nomogram combining deep learning, clinical characteristics and ultrasound features for predicting central lymph node metastasis in papillary …

L Chang, Y Zhang, J Zhu, L Hu, X Wang… - Frontiers in …, 2023 - frontiersin.org
Objective Central lymph node metastasis (CLNM) is a predictor of poor prognosis for
papillary thyroid carcinoma (PTC) patients. The options for surgeon operation or follow-up …

Microwave ablation vs. surgery for papillary thyroid carcinoma with minimal sonographic extrathyroid extension: a multicentre prospective study

L Zheng, J Dou, F Liu, J Yu, Z Cheng, X Yu, H Wang… - European …, 2023 - Springer
Objectives Minimal extrathyroid extension (mETE) was removed from the TNM staging
system. This study was designed prospectively to compare the safety and efficacy of …

[HTML][HTML] Prophylactic central neck dissection for cN0 papillary thyroid carcinoma: is there any difference between western countries and China? A systematic review …

J Yang, Y Han, Y Min, C Chen, J Chen… - Frontiers in …, 2023 - frontiersin.org
Background Recommendations for the performance of prophylactic central neck dissection
(pCND) in patients with clinically node-uninvolved (cN0) papillary thyroid carcinoma (PTC) …