Background Rotavirus results in more diarrhoea‐related deaths in children under five years
than any other single agent in countries with high childhood mortality. It is also a common …

Background As new rotavirus vaccines are being introduced in immunization programs,
global and national estimates of disease burden, especially rotavirus-associated mortality …

Background Rotavirus is the most common cause of severe dehydrating gastroenteritis in
developing countries. Safe, effective, and affordable rotavirus vaccines are needed in these …

Rotaviruses cause life-threatening gastroenteritis in children worldwide; the enormous
disease burden has focused efforts to develop vaccines and led to the discovery of novel …

In 2007, readers of the British Medical Journal voted that the introduction of clean water and
sewerage—the 'sanitation revolution'of the Victorian era—was the most important medical …

Background International postlicensure studies have identified an increased risk of
intussusception after vaccination with the second-generation rotavirus vaccines RotaTeq …

Numerous rotavirus group A (RVA) strains with distinct G-genotype and P-genotype
combinations have been described infecting humans worldwide. However, the increasing …

Background We aimed to assess the efficacy of the oral live attenuated human rotavirus
vaccine Rotarix (RIX4414) for prevention of rotavirus gastroenteritis in European infants …

Vaccination as a deliberate attempt to protect humans against disease has a short history
when measured against the centuries during which man has sought desperately to rid …

Enteric infections, with or without overt diarrhea, have profound effects on intestinal
absorption, nutrition, and childhood development as well as on global mortality. Oral …