Diagnosis, management, and prevention of rotavirus gastroenteritis in children

UD Parashar, EAS Nelson, G Kang - Bmj, 2013 - bmj.com
Rotavirus is the leading cause of severe childhood gastroenteritis. Each year, rotavirus is
responsible for about 25 million clinic visits, two million hospital admissions, and 180 000 …

Intussusception risk and disease prevention associated with rotavirus vaccines in Australia's National Immunization Program

JB Carlin, KK Macartney, KJ Lee… - Clinical Infectious …, 2013 - academic.oup.com
Background. Estimates of the risk of intussusception (IS) associated with currently licensed
rotavirus vaccines (RV1 [Rotarix; GSK] and RV5 [RotaTeq; Merck]) diverge …

[HTML][HTML] Decline in diarrhea mortality and admissions after routine childhood rotavirus immunization in Brazil: a time-series analysis

GMI do Carmo, C Yen, J Cortes, AA Siqueira… - PLoS …, 2011 - journals.plos.org
Background In 2006, Brazil began routine immunization of infants< 15 wk of age with a
single-strain rotavirus vaccine. We evaluated whether the rotavirus vaccination program was …

[HTML][HTML] The clinical development process for a novel preventive vaccine: An overview

K Singh, S Mehta - Journal of postgraduate medicine, 2016 - journals.lww.com
Each novel vaccine candidate needs to be evaluated for safety, immunogenicity, and
protective efficacy in humans before it is licensed for use. After initial safety evaluation in …

Immune responses to rotavirus infection and vaccination and associated correlates of protection

U Desselberger, HI Huppertz - Journal of Infectious Diseases, 2011 - academic.oup.com
Group A rotavirus (RV) strains are a major cause of acute gastroenteritis (AGE) in infants
and young children worldwide [1]. RV disease accounts for more than one-third of all …

Performance of rotavirus vaccines in developed and developing countries

V Jiang, B Jiang, J Tate, UD Parashar, MM Patel - Human vaccines, 2010 - Taylor & Francis
The World Health Organization estimates that rotavirus diarrhea results in approximately half
a million deaths and approximately 2.4 million hospitalizations in developing countries each …

The practice of travel medicine: guidelines by the Infectious Diseases Society of America

DR Hill, CD Ericsson, RD Pearson… - Clinical Infectious …, 2006 - academic.oup.com
Practice of Travel Medicine: Guidelines by the Infectious Diseases Society of America | Clinical
Infectious Diseases | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

[HTML][HTML] Rotavirus diversity and evolution in the post-vaccine world

JT Patton - Discovery medicine, 2012 - ncbi.nlm.nih.gov
Rotaviruses (RVs) are a large genetically diverse population of segmented double-stranded
(ds) RNA viruses that are important causes of gastroenteritis in many animal species. The …

[HTML][HTML] Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine

MM Levine - BMC biology, 2010 - Springer
Oral vaccines, whether living or non-living, viral or bacterial, elicit diminished immune
responses or have lower efficacy in developing countries than in developed countries. Here …

Burden and epidemiology of rotavirus diarrhea in selected African countries: preliminary results from the African Rotavirus Surveillance Network

JM Mwenda, KM Ntoto, A Abebe… - Journal of Infectious …, 2010 - academic.oup.com
Severe rotavirus diarrhea in children< 5 years of age is a major public health problem;
however, limited regional and country specific data on rotavirus disease burden are …