Protective effect of natural rotavirus infection in an Indian birth cohort

BP Gladstone, S Ramani, I Mukhopadhya… - … England Journal of …, 2011 - Mass Medical Soc
Background More than 500,000 deaths are attributed to rotavirus gastroenteritis annually
worldwide, with the highest mortality in India. Two successive, naturally occurring rotavirus …

Evolutionary history and global spread of the emerging G12 human rotaviruses

M Rahman, J Matthijnssens, X Yang, T Delbeke… - Journal of …, 2007 - Am Soc Microbiol
ABSTRACT G12 rotaviruses were first detected in diarrheic children in the Philippines in
1987, but no further cases were reported until 1998. However, G12 rotaviruses have been …

[HTML][HTML] Rotavirus infection in children in Southeast Asia 2008–2018: disease burden, genotype distribution, seasonality, and vaccination

FB Lestari, S Vongpunsawad, N Wanlapakorn… - Journal of biomedical …, 2020 - Springer
Abstract Background Rotaviruses (RVs) are recognized as a major cause of acute
gastroenteritis (AGE) in infants and young children worldwide. Here we summarize the …

Rotavirus incidence and genotype distribution before and after national rotavirus vaccine introduction in Belgium

M Zeller, M Rahman, E Heylen, S De Coster, S De Vos… - Vaccine, 2010 - Elsevier
Rotarix™ was introduced into the Belgian market in 2006 and RotaTeq™ in 2007, quickly
reaching more than 85% vaccine coverage of all newborns in Belgium. The incidence of …

Oral rotavirus vaccines: how well will they work where they are needed most?

M Patel, AL Shane, UD Parashar… - The Journal of …, 2009 - academic.oup.com
Rotavirus vaccines hold promise to decrease the burden of severe diarrhea in the poorest
countries, where 85% of deaths due to rotavirus occur. However, the potency of live oral …

Rotaviruses associate with cellular lipid droplet components to replicate in viroplasms, and compounds disrupting or blocking lipid droplets inhibit viroplasm formation …

W Cheung, M Gill, A Esposito, CF Kaminski… - Journal of …, 2010 - Am Soc Microbiol
Rotaviruses are a major cause of acute gastroenteritis in children worldwide. Early stages of
rotavirus assembly in infected cells occur in viroplasms. Confocal microscopy demonstrated …

What works in fighting diarrheal diseases in developing countries? A critical review

AP Zwane, M Kremer - The World Bank Research Observer, 2007 - academic.oup.com
Abstract The Millennium Development Goals call for reducing by half the proportion of
people without sustainable access to safe drinking water. This goal was adopted in large …

[HTML][HTML] The rotavirus vaccine development pipeline

CD Kirkwood, LF Ma, ME Carey, AD Steele - Vaccine, 2019 - Elsevier
Rotavirus disease is a leading global cause of mortality and morbidity in children under 5
years of age. The effectiveness of the two globally used oral rotavirus vaccines quickly …

Management for intussusception in children

S Gluckman, J Karpelowsky… - Cochrane Database …, 2017 - cochranelibrary.com
Background Intussusception is a common abdominal emergency in children with significant
morbidity. Prompt diagnosis and management reduces associated risks and the need for …

[HTML][HTML] Efficacy of live oral rotavirus vaccines by duration of follow-up: a meta-regression of randomised controlled trials

A Clark, K van Zandvoort, S Flasche… - The Lancet Infectious …, 2019 - thelancet.com
Background The duration of protection offered by rotavirus vaccines varies across the world,
and this variation is important to understanding and predicting the effects of the vaccines …