Head and neck cancer in the elderly: an overview on the treatment modalities

KN Syrigos, D Karachalios, EM Karapanagiotou… - Cancer treatment …, 2009 - Elsevier
The percentage of elderly people with head and neck cancers (HNC) is rising due to
increasing average lifespan. As with younger patients, elderly patients require a …

[HTML][HTML] Radiotherapy controversies and prospective in head and neck cancer: a literature-based critical review

F De Felice, A Polimeni, V Valentini, O Brugnoletti… - Neoplasia, 2018 - Elsevier
In treating head and neck cancer (HNC), the objectives are provided for best functional
results and minimal risk of serious complications. The choice of appropriate management …

[HTML][HTML] Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled …

CM Nutting, JP Morden, KJ Harrington… - The lancet …, 2011 - thelancet.com
Background Xerostomia is the most common late side-effect of radiotherapy to the head and
neck. Compared with conventional radiotherapy, intensity-modulated radiotherapy (IMRT) …

Weekly volume and dosimetric changes during chemoradiotherapy with intensity-modulated radiation therapy for head and neck cancer: a prospective observational …

SA Bhide, M Davies, K Burke, HA McNair… - International Journal of …, 2010 - Elsevier
PURPOSE: The aim of this study was to investigate prospectively the weekly volume
changes in the target volumes and organs at risk and the resulting dosimetric changes …

Monitoring dosimetric impact of weight loss with kilovoltage (kV) cone beam CT (CBCT) during parotid-sparing IMRT and concurrent chemotherapy

KF Ho, T Marchant, C Moore, G Webster… - International Journal of …, 2012 - Elsevier
PURPOSE: Parotid-sparing head-and-neck intensity-modulated radiotherapy (IMRT) can
reduce long-term xerostomia. However, patients frequently experience weight loss and …

Dosimetric explanations of fatigue in head and neck radiotherapy: an analysis from the PARSPORT Phase III trial

SL Gulliford, AB Miah, S Brennan, D McQuaid… - Radiotherapy and …, 2012 - Elsevier
BACKGROUND: An unexpected finding from the phase III parotid sparing radiotherapy trial,
PARSPORT (ISRCTN48243537, CRUK/03/005), was a statistically significant increase in …

Eliminating radiotherapy to the contralateral retropharyngeal and high level II lymph nodes in head and neck squamous cell carcinoma is safe and improves quality of …

CR Spencer, HA Gay, BH Haughey, B Nussenbaum… - Cancer, 2014 - Wiley Online Library
BACKGROUND Radiation treatment volumes in head and neck squamous cell carcinoma
(HNSCC) are controversial. The authors report the outcomes, patterns of failure, and quality …

Novel approaches to improve the therapeutic index of head and neck radiotherapy: an analysis of data from the PARSPORT randomised phase III trial

F Buettner, AB Miah, SL Gulliford, E Hall… - Radiotherapy and …, 2012 - Elsevier
PURPOSE: Subjective xerostomia is a common side-effect following radiotherapy for the
treatment of head-and-neck cancer. Standard mean dose models previously used to model …

NIMRAD–a phase III trial to investigate the use of nimorazole hypoxia modification with intensity-modulated radiotherapy in head and neck cancer

D Thomson, H Yang, H Baines, E Miles… - Clinical …, 2014 - clinicaloncologyonline.net
NIMRAD is a randomised placebo-controlled trial of synchronous nimorazole versus
radiotherapy alone in patients with locally advanced head and neck oropharyngeal …

The value of magnetic resonance imaging in target volume delineation of base of tongue tumours–a study using flexible surface coils

M Ahmed, M Schmidt, A Sohaib, C Kong… - Radiotherapy and …, 2010 - Elsevier
INTRODUCTION: Magnetic resonance imaging (MRI) provides superior diagnostic accuracy
over computed tomography (CT) in oropharyngeal tumours. Precise delineation of the gross …