Cardiovascular disease in patients with severe mental illness

RE Nielsen, J Banner, SE Jensen - Nature Reviews Cardiology, 2021 - nature.com
Individuals diagnosed with schizophrenia or bipolar disorder have a life expectancy 15–20
years shorter than that in the general population. The rate of unnatural deaths, such as …

[HTML][HTML] All-cause and cause-specific mortality among people with bipolar disorder: a large-scale systematic review and meta-analysis

TB Biazus, GH Beraldi, L Tokeshi, LS Rotenberg… - Molecular …, 2023 - nature.com
Objective Bipolar disorder (BD) is associated with premature mortality. All-cause and
specific mortality risks in this population remain unclear, and more studies are still needed to …

Mental health status of individuals with a mood-disorder during the COVID-19 pandemic in Australia: Initial results from the COLLATE project

TE Van Rheenen, D Meyer, E Neill, A Phillipou… - Journal of affective …, 2020 - Elsevier
Background Physical-distancing strategies during the coronavirus (COVID-19) pandemic
may be particularly detrimental to the mental health of individuals with a pre-existing mood …

The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management

RS McIntyre, M Alda, RJ Baldessarini, M Bauer… - World …, 2022 - Wiley Online Library
Bipolar disorder is heterogeneous in phenomenology, illness trajectory, and response to
treatment. Despite evidence for the efficacy of multimodality interventions, the majority of …

[HTML][HTML] Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity

O Bondareva, JR Rodríguez-Aguilera, F Oliveira… - Nature …, 2022 - nature.com
Obesity promotes diverse pathologies, including atherosclerosis and dementia, which
frequently involve vascular defects and endothelial cell (EC) dysfunction. Each organ has …

[HTML][HTML] Obesity and brain structure in schizophrenia–ENIGMA study in 3021 individuals

SR McWhinney, K Brosch, VD Calhoun… - Molecular …, 2022 - nature.com
Schizophrenia is frequently associated with obesity, which is linked with neurostructural
alterations. Yet, we do not understand how the brain correlates of obesity map onto the brain …

[HTML][HTML] Coronary heart disease and depression or anxiety: a bibliometric analysis

Y Zhou, XP Zhu, JJ Shi, GZ Yuan, ZA Yao… - Frontiers in …, 2021 - frontiersin.org
This study aimed to conduct a bibliometric analysis of published studies on the association
between coronary heart disease (CHD) and depression or anxiety. The study also aimed to …

Obesity as a risk factor for accelerated brain ageing in first-episode psychosis—a longitudinal study

S McWhinney, M Kolenic, K Franke… - Schizophrenia …, 2021 - academic.oup.com
Background Obesity is highly prevalent in schizophrenia, with implications for psychiatric
prognosis, possibly through links between obesity and brain structure. In this longitudinal …

[HTML][HTML] Association between body mass index and subcortical brain volumes in bipolar disorders–ENIGMA study in 2735 individuals

SR McWhinney, C Abé, M Alda, F Benedetti… - Molecular …, 2021 - nature.com
Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often
associated with neurostructural alterations. Yet, the effects of obesity on brain structure in BD …

Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants

SR McWhinney, C Abé, M Alda, F Benedetti… - Psychological …, 2023 - cambridge.org
Background: Obesity is highly prevalent and disabling, especially in individuals with severe
mental illness including bipolar disorders (BD). The brain is a target organ for both obesity …