Mitophagy is an evolutionarily conserved process involving the autophagic targeting and
clearance of mitochondria destined for removal. Recent insights into the complex nature of …

Aging is the time-dependent process that all living organisms go through characterized by
declining physiological function due to alterations in metabolic and molecular pathways …

Mitochondria ensure the supply of cellular energy through the production of ATP via
oxidative phosphorylation. The alteration of this process, called mitochondrial dysfunction …

Cardiovascular disease (CVD) is one of the predominant causes of death and morbidity.
Mitochondria play a key role in maintaining cardiac energy metabolism. However …

The association of airborne particulate matter exposure with the deteriorating function of the
cardiovascular system is fundamentally driven by the impairment of mitochondrial-nuclear …

Multicellular organisms are complex biological systems, composed of specialized tissues
that require coordination of the metabolic and fitness state of each component. In the cells …

Compromised mitophagy and mitochondrial homeostasis are major contributors for the
etiology of cardiac aging, although the precise underlying mechanisms remains elusive …

According to the latest Global Burden of Disease Study, cardiovascular disease (CVD) is the
leading cause of death, and ischemic heart disease and stroke are the cause of death in …

Mitophagy is a specific autophagic phenomenon in which damaged or redundant
mitochondria are selectively cleared by autophagic lysosomes. A decrease in mitophagy …

Long non-coding RNAs (lncRNAs) are non-coding RNAs with lengths> 200 nt and are
involved in the occurrence and development of cardiovascular diseases (CVDs). Exosomes …