Bone fractures and critical-size bone defects are significant public health issues, and clinical
treatment outcomes are closely related to the intrinsic properties of the utilized implant …

The clinical injury of bone and cartilage tissue is complex and specific, posing a significant
threat to human health as traditional regenerative therapies (including autograft and allograft …

Insufficient antibacterial effects and over-fast degradation are the main limitations of
magnesium (Mg)-based orthopedic implants. In this study, a sandwiched composite coating …

Vertebral compression fractures (VCFs) are common in osteoporotic patients, with a
frequency projected to increase alongside a growing geriatric population. VCFs often result …

Titanium (Ti) alloys have been widely applied clinically due to their good biocompatibility,
corrosion resistance and mechanical stability. However, how to improve the weak …

Insufficient initial vascularization plays a pivotal role in the ineffectiveness of bone
biomaterials for treating bone defects. Consequently, enhancing the angiogenic properties …

Osteoporosis (OP) is a systemic metabolic bone disease characterized by low bone mass,
damage to bone microstructure and increased bone fragility. The imbalance of functional …

Bone tissue defects have emerged as a significant health concern, impacting individuals'
overall well-being and daily functionality. The implantation of scaffold materials for bone …

Regeneration of large bone defects remains a major clinical challenge due to the lack of
vasculature and innervation. Few studies have focused on the regeneration of all three …

Overall, 12% of the global population (800 million) suffers from liver disease, which causes 2
million deaths every year. Liver injury involving characteristic reactive oxygen/nitrogen …