Even given recent advances in nanomedicine development of breast cancer treatment in
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy that is
characterized by early metastasis, low resectability, high recurrence, and therapy resistance …

The efficacy of standard glioblastoma (GBM) treatments has been limited due to the highly
immunosuppressive tumor immune microenvironment, interpatient tumor heterogenicity and …

Nanoparticles (NPs) that permit active targeting promise to play a key role in cancer therapy
moving forward. However, in order to successfully advance into clinic, these delivery …

Abstract Fibroblast growth factors 9 (FGF9) modulates cell proliferation, differentiation and
motility for development and repair in normal cells. Abnormal activation of FGF9 signaling is …

Exercise training reduces the incidence of several cancers, but the mechanisms underlying
these effects are not fully understood. Exercise training can affect the spleen function, which …

Several proteins and peptides have therapeutic potential and can be used for cancer
therapy. By binding to cell surface receptors and other indicators uniquely linked with or …

Background The antiprostate cancer effects of dietary ω-3 fatty acids (FAs) were previously
found to be dependent on host G-protein coupled receptor 120 (GPR120). Using an …

Introduction Computational models yield valuable insights into biological interactions not
fully elucidated by experimental approaches. This study investigates an innovative …

Renal cell carcinoma (RCC) is the deadliest form of urological cancer and is projected to be
the fourth most common neoplasm in the USA in males by 2040. In addition to the current …