Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …

Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

The amount of research activity concerning α‐methylene‐γ‐butyrolactones and α‐alkylidene‐
γ‐butyrolactones has increased dramatically in recent years. This Review summarizes the …

Artemisia annua L.(Chinese wormwood herb, Asteraceae) synthesizes artemisinin, which is
known as qinghaosu, considers as a unique sesquiterpene endoperoxide lactone. In …

Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about
chemical residues in animal products and the environment are driving the development of …

The Ambrosia species represent one of the most problematic groups of invasive weeds
around the world. The ease with which they are introduced and spread in new countries …

Potential toxicity, costs, and drug‐resistant pathogens necessitate the development of new
antileishmanial agents. Medicinal and aromatic plants constitute a major source of natural …

Lactones are among the well-known organic substances with a specific taste and smell.
They are characterized by antibacterial, antiviral, anti-inflammatory, and anti-cancer …

Background: The spirocyclic compounds have always aroused a great interest because this
motif is present as structural core in a number of natural products and bioactive compounds …

Leishmaniasis and Chagas disease remain a significant global problem. Current treatments
have serious disadvantage due to cost, toxicity, long therapy duration and resistance. In the …