Recent advances in circadian-regulated pharmacokinetics and its implications for chronotherapy
F Yu, Y Liu, R Zhang, L Zhu, T Zhang, Y Shi - Biochemical Pharmacology, 2022 - Elsevier
Dependence of pharmacokinetics and drug effects (efficacy and toxicity) on dosing time has
long been recognized. However, significant progress has only recently been made in our …
long been recognized. However, significant progress has only recently been made in our …
Pharmacokinetics-based chronotherapy
Dosing time-dependency of pharmacokinetics (or chronopharmacokinetics) has been long
recognized. Studies in recent years have revealed that daily rhythmicity in expression of …
recognized. Studies in recent years have revealed that daily rhythmicity in expression of …