Treatment of obesity: weight loss and bariatric surgery

BM Wolfe, E Kvach, RH Eckel - Circulation research, 2016 - Am Heart Assoc
This review focuses on the mechanisms underlying, and indications for, bariatric surgery in
the reduction of cardiovascular disease (CVD), as well as other expected benefits of this …

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis

C Crewe, YA An, PE Scherer - The Journal of clinical …, 2017 - Am Soc Clin Investig
There are three dominant contributors to the pathogenesis of dysfunctional adipose tissue
(AT) in obesity: unresolved inflammation, inappropriate extracellular matrix (ECM) …

Obesity and preeclampsia: common pathophysiological mechanisms

P Lopez-Jaramillo, J Barajas… - Frontiers in …, 2018 - frontiersin.org
Preeclampsia is a disorder specific of the human being that appears after 20 weeks of
pregnancy, characterized by new onset of hypertension and proteinuria. Abnormal …

Effects of high-intensity interval training and moderate-intensity continuous training on endothelial function and cardiometabolic risk markers in obese adults

BJ Sawyer, WJ Tucker, DM Bhammar… - Journal of Applied …, 2016 - journals.physiology.org
We hypothesized that high-intensity interval training (HIIT) would be more effective than
moderate-intensity continuous training (MICT) at improving endothelial function and …

[PDF][PDF] Obesity treatment: Weight loss versus increasing fitness and physical activity for reducing health risks

GA Gaesser, SS Angadi - Iscience, 2021 - cell.com
We propose a weight-neutral strategy for obesity treatment on the following grounds:(1) the
mortality risk associated with obesity is largely attenuated or eliminated by moderate-to-high …

Coronary vascular regulation, remodelling, and collateralization: mechanisms and clinical implications on behalf of the working group on coronary pathophysiology …

AR Pries, L Badimon, R Bugiardini… - European heart …, 2015 - academic.oup.com
Histological specimen and textbook schematics evoke static pictures of vascular networks.
However, the concept of a static system is grossly misleading as vessels and their …

Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing

DGA Burton, RGA Faragher - Biogerontology, 2018 - Springer
Cellular senescence is now considered as a major mechanism in the development and
progression of various diseases and this may include metabolic diseases such as obesity …

[HTML][HTML] The endothelial glycocalyx: a possible therapeutic target in cardiovascular disorders

A Milusev, R Rieben, N Sorvillo - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
The physiological, anti-inflammatory, and anti-coagulant properties of endothelial cells
(ECs) rely on a complex carbohydrate-rich layer covering the luminal surface of ECs, called …

Association between aerobic exercise training effects of serum adropin level, arterial stiffness, and adiposity in obese elderly adults

S Fujie, N Hasegawa, T Kurihara… - Applied Physiology …, 2017 - cdnsciencepub.com
Serum levels of adropin, which enhances endothelial cell release of nitric oxide (NO), are
lower in obese patients. Although habitual aerobic exercise reduces arterial stiffness and …

Position paper of the European Society of Cardiology–working group of coronary pathophysiology and microcirculation: obesity and heart disease

L Badimon, R Bugiardini, E Cenko… - European heart …, 2017 - academic.oup.com
The epidemic of obesity is recognized as one of the most important public health problems
facing the world today. According to 2014 World Health Organization (WHO) data, 1 39% of …