[HTML][HTML] Supramolecular biomaterials for cancer immunotherapy

H Liang, Q Lu, J Yang, G Yu - Research, 2023 - spj.science.org
Cancer immunotherapy has achieved tremendous successful clinical results and obtained
historic victories in tumor treatments. However, great limitations associated with feeble …

Bioinspired chiral nanozymes: Synthesis strategies, classification, biological effects and biomedical applications

X Zhang, Z An, J An, X Tian - Coordination Chemistry Reviews, 2024 - Elsevier
Chiral nanozymes represent an exciting convergence of nanotechnology and enzymatic
catalysis, possessing both the biologically inspired catalytic properties of nanomaterials and …

Tumor microenvironment‐responsive nanoparticles amplifying STING signaling pathway for cancer immunotherapy

D Liu, S Liang, K Ma, QF Meng, X Li, J Wei… - Advanced …, 2024 - Wiley Online Library
Insufficient activation of the stimulator of interferon genes (STING) signaling pathway and
profoundly immunosuppressive microenvironment largely limits the effect of cancer …

“Spark” PtMnIr Nanozymes for Electrodynamic‐Boosted Multienzymatic Tumor Immunotherapy

D Li, E Ha, Z Zhou, J Zhang, Y Zhu, F Ai… - Advanced …, 2024 - Wiley Online Library
Multienzyme‐mimicking redox nanozymes capable of efficient reactive oxygen species
(ROS) generation and cellular homeostasis disruption are highly pursued for cancer …

Orchestrated cytosolic delivery of antigen and adjuvant by manganese ion-coordinated nanovaccine for enhanced cancer immunotherapy

ZL Gao, W Xu, SJ Zheng, QJ Duan, R Liu, JZ Du - Nano Letters, 2023 - ACS Publications
Cancer vaccines have received tremendous attention in cancer immunotherapy due to their
capability to induce a tumor-specific immune response. However, their effectiveness is …

[HTML][HTML] Nanomaterials: small particles show huge possibilities for cancer immunotherapy

Z Chen, Z Yue, K Yang, S Li - Journal of Nanobiotechnology, 2022 - Springer
With the economy's globalization and the population's aging, cancer has become the
leading cause of death in most countries. While imposing a considerable burden on society …

Allomelanin-based biomimetic nanotherapeutics for orthotopic glioblastoma targeted photothermal immunotherapy

M Sun, Y Li, W Zhang, X Gu, R Wen, K Zhang, J Mao… - Acta Biomaterialia, 2023 - Elsevier
Immune checkpoint blockade (ICB) therapy has shown great potential in the treatment of
malignant tumors, but its therapeutic effect on glioblastoma (GBM) is unsatisfactory because …

Manganese@ Albumin Nanocomplex and Its Assembled Nanowire Activate TLR4‐Dependent Signaling Cascades of Macrophages

S Huang, Y Gao, H Li, R Wang, X Zhang… - Advanced …, 2024 - Wiley Online Library
The immunomodulatory effect of divalent manganese cations (Mn2+), such as activation of
the cGAS− STING pathway or NLRP3 inflammasomes, positions them as adjuvants for …

Dual-pathway STING activation and chemodynamic therapy for improved anti-tumor therapy

W Xu, L Qiao, Z Wang, Y Qian, L Li, Q Sun… - Chemical Engineering …, 2023 - Elsevier
The cyclic-GMP-AMP synthetase stimulator of interferon genes (cGAS-STING) pathway is a
naturally occurring immune pathway activated by cytosolic DNA. The end products of this …

Ultra-efficient radio-immunotherapy for reprogramming the hypoxic and immunosuppressive tumor microenvironment with durable innate immune memory

J Yang, C Zhang, X Chen, D Zhou, Z Sun, R Niu, Y Zhu… - Biomaterials, 2023 - Elsevier
Radiosensitization efficacy of conventional tumor radiosensitizers has been frequently
limited by insufficient competence for tumor microenvironment (TME) regulation and …