[HTML][HTML] CTCF-mediated 3D chromatin predetermines the gene expression program in the male germline
Y Kitamura, K Takahashi, S Maezawa, Y Munakata… - Biorxiv, 2023 - ncbi.nlm.nih.gov
Spermatogenesis is a unidirectional differentiation process that generates haploid sperm,
but how the gene expression program that directs this process is established is largely …
but how the gene expression program that directs this process is established is largely …
[HTML][HTML] Stage-specific dynamic reorganization of genome topology shapes transcriptional neighborhoods in developing human retinal organoids
We have generated a high-resolution Hi-C map of developing human retinal organoids to
elucidate spatiotemporal dynamics of genomic architecture and its relationship with gene …
elucidate spatiotemporal dynamics of genomic architecture and its relationship with gene …
[HTML][HTML] 动物早期胚胎发育中表观重编程的机制
余彤， 任斌斌， 郑睿智， 朱文治， 苏建民 - 畜牧兽医学报, 2023 - html.rhhz.net
哺乳动物早期胚胎发育过程中, 受精卵经历了一系列表观遗传重编程事件,
去除了雌雄原核的表观遗传记忆, 从而建立了胚胎的全能性. 然而, 这些重编程事件的进行必须 …
去除了雌雄原核的表观遗传记忆, 从而建立了胚胎的全能性. 然而, 这些重编程事件的进行必须 …