Background Lower urinary tract syndrome (LUTS) is a group of urinary tract symptoms and
signs that can include urinary incontinence. Advancing age is a major risk factor for LUTS; …

Prior studies suggest that urothelium-released adenosine 5′-triphosphate (ATP) has a
prominent role in bladder mechanotransduction. Urothelial ATP regulates the micturition …

The urinary bladder requires adequate concentrations of extracellular adenosine 5′-
triphosphate (ATP) and other purines at receptor sites to function properly. Sequential …

Background: The endogenous purine 8-aminoguanine induces diuresis/natriuresis/
glucosuria by inhibiting PNPase (purine nucleoside phosphorylase); however, mechanistic …

Adenosine 5′-triphosphate (ATP) is released in the bladder lumen during filling. Urothelial
ATP is presumed to regulate bladder excitability. Urinary ATP is suggested as a urinary …

In this paper, a sensitive method for the determination of 3-chloro-1, 2-propanediol (3-
MCPD) by high performance liquid chromatography-fluorescence detection (HPLC-FLD) …

Acute kidney injury (AKI) is common in patients hospitalized for COVID-19, complicating
their clinical course and contributing to worse outcomes. Animal studies show that …

Mouse T cells express the ecto-ADP-ribosyltransferase ARTC2. 2, which can transfer the
ADP-ribose group of extracellular nicotinamide adenine dinucleotide (NAD+) to arginine …

The vesicular nucleotide transporter (VNUT) is critical for sympathetic co-transmission and
purinergic transmission maintenance. To examine this proposal, we assessed whether the …

Background Immunosuppression is a hallmark of cancer progression. Tumor-derived small
extracellular vesicles (sEV), also known as TEX, produce adenosine (ADO) and can mediate …