Mature mouse oocytes that have received the nuclei of pachytene primary spermatocytes (or
metaphase I chromosomes of primary spermatocytes) can develop into fertile offspring …

Recent results in animals and plants have shown a strong link between DNA methylation,
chromatin structure and epigenetic control. In plants DNA methylation affects both symmetric …

Neural tube closure (neurulation) is a complex process involving many cell phenomena.
Both extrinsic and intrinsic forces are essential to elevate the neural plate into the neural …

Dichloroacetic acid (DCA) and trichloroacetic acid (TCA) are found in drinking water and are
metabolites of trichloroethylene. They are carcinogenic and promote liver tumors in B6C3F1 …

The different fragmentation channels of cytosine, adenine and guanine have been studied
through DFT calculations. The electronic structure of bases, their cations, and the fragments …

In situ alterations of DNA methylation were studied between 14 d postcoitum and 4 d
postpartum in Sertoli cells and germ cells from mouse testis, using anti-5-methylcytosine …

This study was set to investigate whether the adverse effects of heat on spermatozoa and
subsequent foetuses could be prevented by long‐term zinc administration. The scrotums of …

It has recently been shown that in Xenopus, DNA demethylation at promoter regions may
involve protein-DNA interactions, based on the specificity of the demethylated sites. Utilizing …

We have previously purified and characterized a 5-methylcytosine (5-MeC)-DNA
glycosylase from 12 day old chick embryos [Jost, JP et al.(1995) J. Biol. Chem. 270, 9734 …

There is an abundant amount of information on the mechanisms of action of genotoxic
chemicals that act as carcinogens and the role that mutations play in carcinogenesis …