PD-1/PD-L1 checkpoint inhibitors in tumor immunotherapy

J Liu, Z Chen, Y Li, W Zhao, JB Wu… - Frontiers in …, 2021 - frontiersin.org
Programmed death protein 1 (PD1) is a common immunosuppressive member on the
surface of T cells and plays an imperative part in downregulating the immune system and …

Pathology of triple negative breast cancer

F Borri, A Granaglia - Seminars in cancer biology, 2021 - Elsevier
Triple negative breast cancer (TNBC) is a subtype of breast tumor lacking hormone
receptors expression and HER2 gene amplification and represents 24% of newly diagnosed …

Federated learning for predicting histological response to neoadjuvant chemotherapy in triple-negative breast cancer

J Ogier du Terrail, A Leopold, C Joly, C Béguier… - Nature medicine, 2023 - nature.com
Triple-negative breast cancer (TNBC) is a rare cancer, characterized by high metastatic
potential and poor prognosis, and has limited treatment options. The current standard of …

The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer

X Zheng, M Huang, L Xing, R Yang, X Wang, R Jiang… - Molecular cancer, 2020 - Springer
Background Increasing studies have shown that circRNA is closely related to the
carcinogenesis and development of many cancers. However, biological functions and the …

N6-methyladenosine METTL3 promotes cervical cancer tumorigenesis and Warburg effect through YTHDF1/HK2 modification

Q Wang, X Guo, L Li, Z Gao, X Su, M Ji, J Liu - Cell death & disease, 2020 - nature.com
Abstract N6-methyladenosine (m6A) serves as the most common and conserved internal
transcriptional modification. However, the roles of m6A on cervical cancer (CC) …

Nano-ultrasonic contrast agent for chemoimmunotherapy of breast cancer by immune metabolism reprogramming and tumor autophagy

X Yang, M Zhao, Z Wu, C Chen, Y Zhang, L Wang… - ACS …, 2022 - ACS Publications
The functional status of innate immune cells is a considerable determinant of effective
antitumor immune response. However, the triple-negative breast cancer tumor …

Triple‑negative breast cancer: A run‑through of features, classification and current therapies

M Manjunath, B Choudhary - Oncology Letters, 2021 - spandidos-publications.com
Breast cancer is the most prevalent cancer in women worldwide. Triple‑negative breast
cancer (TNBC) is characterized by the lack of expression of estrogen receptor, progesterone …

Targeted therapy and drug resistance in triple-negative breast cancer: the EGFR axis

S Lev - Biochemical Society Transactions, 2020 - portlandpress.com
Targeting of estrogen receptor is commonly used as a first-line treatment for hormone-
positive breast cancer patients, and is considered as a keystone of systemic cancer therapy …

Triple negative breast cancer and non-small cell lung cancer: Clinical challenges and nano-formulation approaches

S Ghosh, A Javia, S Shetty, D Bardoliwala… - Journal of Controlled …, 2021 - Elsevier
Triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC) are amongst
the most aggressive forms of solid tumors. TNBC is highlighted by absence of genetic …

Co‐delivery CPT and PTX prodrug with a photo/thermo‐responsive nanoplatform for triple‐negative breast cancer therapy

W Zhou, X Ma, J Wang, X Xu, O Koivisto… - Smart …, 2022 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is still the most aggressive cancer in women.
Combination chemotherapy holds great potential for cancer therapy; however, the off‐target …