Targeted liposomal chemotherapies to treat triple-negative breast cancer
Simple Summary Triple-negative breast cancers (TNBCs) are mainly treated with standard
chemotherapies. Combined therapies have been demonstrated as a promising treatment …
chemotherapies. Combined therapies have been demonstrated as a promising treatment …
Quantitative analysis of tyrosine phosphorylation from FFPE tissues reveals patient-specific signaling networks
IN Kohale, DM Burgenske, AC Mladek, KK Bakken… - Cancer research, 2021 - AACR
Human tissue samples commonly preserved as formalin-fixed paraffin-embedded (FFPE)
tissues after diagnostic or surgical procedures in the clinic represent an invaluable source of …
tissues after diagnostic or surgical procedures in the clinic represent an invaluable source of …
Molecular pathways and therapeutic targets linked to triple-negative breast cancer (TNBC)
Cancer is a group of diseases characterized by uncontrolled cellular growth, abnormal
morphology, and altered proliferation. Cancerous cells lose their ability to act as anchors …
morphology, and altered proliferation. Cancerous cells lose their ability to act as anchors …
Metabolic Signatures of Tumor Responses to Doxorubicin Elucidated by Metabolic Profiling in Ovo
IW Achkar, S Kader, SS Dib, K Junejo, SB Al-Bader… - Metabolites, 2020 - mdpi.com
Background: Dysregulated cancer metabolism is associated with acquired resistance to
chemotherapeutic treatment and contributes to the activation of cancer survival mechanisms …
chemotherapeutic treatment and contributes to the activation of cancer survival mechanisms …
Coordinated modulation of long non-coding RNA ASBEL and curcumin co-delivery through multicomponent nanocomplexes for synchronous triple-negative breast …
X He, F Lin, R Jia, Y Xia, Z Liang, X Xiao, Q Hu… - Journal of …, 2023 - Springer
Background Abnormally regulated long non-coding RNAs (lncRNAs) functions in cancer
emphasize their potential to serve as potential targets for cancer therapeutic intervention …
emphasize their potential to serve as potential targets for cancer therapeutic intervention …
Multicomponent-assembled nanodiamond hybrids for targeted and imaging guided triple-negative breast cancer therapy via a ternary collaborative strategy
X Cui, X Deng, Z Liang, J Lu, L Shao, X Wang… - Biomaterials …, 2021 - pubs.rsc.org
Uniting combinational strategies has been confirmed to be a robust choice for high-
performance cancer treatment due to their abilities to overcome tumor heterogeneity and …
performance cancer treatment due to their abilities to overcome tumor heterogeneity and …
[HTML][HTML] Thioridazine combined with carboplatin results in synergistic inhibition of triple negative breast cancer by targeting cancer stem cells
Y Wang, L Xia, J Lin, L Gong, Y Xia, Y Xu, L Liu… - Translational …, 2022 - Elsevier
Cancer stem cells (CSCs) in triple-negative breast cancer (TNBC) are closely related to
tumorigenesis and metastasis. Thioridazine (THZ) is a usual phenothiazine antipsychotic …
tumorigenesis and metastasis. Thioridazine (THZ) is a usual phenothiazine antipsychotic …
Immobilized doxorubicin and ribociclib carbamate linkers encaged in surface modified cubosomes spatially target tumor reductive environment to enhance antitumor …
In the present investigation, we have strategically synthesized Glutathione (GSH) stimuli-
sensitive analogues using carbamate linkers (CL) of DOX (DOX-CL) and RB (RB-CL) which …
sensitive analogues using carbamate linkers (CL) of DOX (DOX-CL) and RB (RB-CL) which …
[HTML][HTML] Bioinformatics analysis of key genes in triple negative breast cancer and validation of oncogene PLK1
Y Ren, R Deng, Q Zhang, J Li, B Han… - Annals of translational …, 2020 - ncbi.nlm.nih.gov
Background Breast cancer is the most common malignancy in women. Triple-negative
breast cancer (TNBC) refers to a special subtype that is deficient in the expression of …
breast cancer (TNBC) refers to a special subtype that is deficient in the expression of …
Triazole‐tethered boswellic acid derivatives against breast cancer: Synthesis, in vitro, and in‐silico studies
A series of new analogues of 3-O-acetyl-11-keto-β-boswellic acid (β-AKBA, 1), 3-O-acetyl-β-
boswellic acid (β-ABA, 2)(3–8) and 1H-1, 2, 3-triazole hybrids of β-AKBA (10a-j) were …
boswellic acid (β-ABA, 2)(3–8) and 1H-1, 2, 3-triazole hybrids of β-AKBA (10a-j) were …