[HTML][HTML] Triple-negative breast cancer comparison with canine mammary tumors from light microscopy to molecular pathology

AA Namagerdi, D d'Angelo, F Ciani… - Frontiers in …, 2020 - ncbi.nlm.nih.gov
Many similar characteristics in human and dog cancers including, spontaneous
development, clinical presentation, tumor heterogeneity, disease progression, and response …

Cadinane-type sesquiterpenoid dimeric diastereomers hibisceusones AC from infected stems of Hibiscus tiliaceus with cytotoxic activity against triple-negative breast …

DL Chen, GX Ma, EL Yang, Y Yang, CH Wang… - Bioorganic …, 2022 - Elsevier
Three new cadinane-type sesquiterpenoid dimeric diastereomers (1–3) named
hibisceusones AC were obtained from the infected stems of Hibiscus tiliaceus. The …

Design and validation of nanofibers made of self-assembled peptides to become multifunctional stimuli-sensitive nanovectors of anticancer drug doxorubicin

V Del Genio, A Falanga, E Allard-Vannier… - Pharmaceutics, 2022 - mdpi.com
Self-assembled peptides possess remarkable potential as targeted drug delivery systems
and key applications dwell anti-cancer therapy. Peptides can self-assemble into …

[HTML][HTML] IMMUNEPOTENT CRP plus doxorubicin/cyclophosphamide chemotherapy remodel the tumor microenvironment in an air pouch triple-negative breast cancer …

SE Santana-Krímskaya, MA Franco-Molina… - Biomedicine & …, 2020 - Elsevier
Abstract In 1889, Steven Paget postulated the theory that cancer cells require a permissive
environment to grow. This permissive environment is known as the tumor microenvironment …

Specific roles of HSP27 S15 phosphorylation augmenting the nuclear function of HER2 to promote trastuzumab resistance

SY Hwang, SK Choi, SH Seo, H Jo, JH Shin, Y Na… - Cancers, 2020 - mdpi.com
Trastuzumab (TZMB) is widely used as first line therapy for breast cancer (BC) patients
overexpressing human epidermal growth factor receptor 2 (HER2). Despite its clinical …

Chemotherapy options beyond the first line in HER‐negative metastatic breast cancer

V Lorusso, A Latorre, F Giotta - Journal of Oncology, 2020 - Wiley Online Library
Despite the recent advances in the biological understanding of breast cancer (BC),
chemotherapy still represents a key component in the armamentarium for this disease …

Biomimetic “nano-spears” for CAFs-targeting: splintered three “shields” with enhanced cisplatin anti-TNBC efficiency

Y Wu, R Chen, S Ni, K Hu - Journal of Controlled Release, 2024 - Elsevier
The treatment dilemma of triple-negative breast cancer (TNBC) revolves around drug
resistance and metastasis. Cancer-associated fibroblasts (CAFs) contribute to cisplatin (Cis) …

Chemotherapeutic effect of stigmasterol in sorafenib treated breast cancer cell lines via modulation of NF-κB and ERK signaling pathways

G Omran, M Abd-Alhaseeb… - Egyptian Journal of …, 2024 - journals.ekb.eg
AbstractBreast cancer is the main predisposing factor for female tumor-related death
globally, which increases the requirement to investigate the effectiveness of new drug …

Colchicine-binding site agent CH-2-77 as a potent tubulin inhibitor suppressing triple-negative breast cancer

S Deng, RI Krutilina, KL Hartman, H Chen… - Molecular cancer …, 2022 - AACR
Triple-negative breast cancer (TNBC) is a highly aggressive type of breast cancer. Unlike
other subtypes of breast cancer, TNBC lacks hormone and growth factor receptor targets …

[HTML][HTML] Establishment and verification of a nomogram to predict tumor-specific mortality risk in triple-negative breast cancer: a competing risk model based on the …

Z Li, Y Shi, L Wu, H Zhang, J Xue, W Li, X Wang… - Gland …, 2022 - ncbi.nlm.nih.gov
Background Triple-negative breast cancer (TNBC) is the subtype of breast cancer with the
worst prognosis, and traditional survival analysis methods are biased when predicting …