Collaborative federated learning behind hospitals' firewalls for predicting histological response to neoadjuvant chemotherapy in triple-negative breast cancer

JO Du Terrail, A Leopold, C Joly, C Beguier, M Andreux… - medRxiv, 2021 - medrxiv.org
1 Abstract Triple-Negative Breast Cancer (TNBC) is a rare cancer, characterized by high
metastatic potential and poor prognosis, and has limited treatment options compared to …

A Drug Molecule-Modified Graphene Field-Effect Transistor Nanosensor for Rapid, Label-Free, and Ultrasensitive Detection of Estrogen Receptor α Protein

P Ming, J Li, L Yang, Y Yu, L Tang, H Zhou… - Analytical …, 2024 - ACS Publications
Estrogen receptor α (ERα) is an important biomarker in breast cancer diagnosis and
treatment. Sensitive and accurate detection of ERα protein expression is crucial in guiding …

Radiomics in triple negative breast cancer: new horizons in an aggressive subtype of the disease

CC Mireștean, C Volovăț, RI Iancu… - Journal of Clinical …, 2022 - mdpi.com
In the last decade, the analysis of the medical images has evolved significantly, applications
and tools capable to extract quantitative characteristics of the images beyond the …

Aptamer-functionalized triptolide with release controllability as a promising targeted therapy against triple-negative breast cancer

Y Chen, J Yang, C Wang, T Wang, Y Zeng, X Li… - Journal of Experimental …, 2024 - Springer
Targeted delivery and precise release of toxins is a prospective strategy for the treatment of
triple-negative breast cancer (TNBC), yet the flexibility to incorporate both properties …

Triple-negative breast cancer comparison with canine mammary tumors from light microscopy to molecular pathology

A Amirkhani Namagerdi, D d'Angelo, F Ciani… - Frontiers in …, 2020 - frontiersin.org
Many similar characteristics in human and dog cancers including, spontaneous
development, clinical presentation, tumor heterogeneity, disease progression, and response …

Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth

A Cheung, AM Chenoweth, A Johansson… - Clinical Cancer …, 2024 - AACR
Purpose: Anti-EGFR antibodies show limited response in breast cancer, partly due to
activation of compensatory pathways. Furthermore, despite the clinical success of cyclin …

CXCL8 facilitates the survival and Paclitaxel-resistance of triple-negative breast cancers

M Yi, C Peng, B Xia, L Gan - Clinical Breast Cancer, 2022 - Elsevier
Background This study aimed to demonstrate CXCL8 expression in TNBC tissues and cells,
and elucidate the functional mechanism of CXCL8 in paclitaxel (PTX)-resistant TNBC …

Rare Earth Nanoprobes for Targeted Delineation of Triple Negative Breast Cancer and Enhancement of Radioimmunotherapy

ZH Ming, YQ Zhang, L Song, M Chen, LL Lin… - Advanced …, 2024 - Wiley Online Library
Radiotherapy demonstrates a synergistic effect with immunotherapy by inducing a
transformation of “immune cold” tumors into “immune hot” tumors in triple negative breast …

Cytotoxic evaluation of YSL-109 in a triple negative breast cancer cell line and toxicological evaluations

Y Sixto-López, C Ordaz-Pichardo… - Naunyn-Schmiedeberg's …, 2023 - Springer
Breast cancer (BC) is the leading cause of cancer-related death in women worldwide. Triple
negative breast cancer (TNBC) is the most aggressive form of BC being with the worst …

Tuning Peptide-Based Nanofibers for Achieving Selective Doxorubicin Delivery in Triple-Negative Breast Cancer

R Bellavita, M Piccolo, L Leone… - International Journal …, 2024 - Taylor & Francis
Introduction The design of delivery tools that efficiently transport drugs into cells remains a
major challenge in drug development for most pathological conditions. Triple-negative …